Sunscreen compositions and methods of use thereof
Disclosed herein are novel methods for reducing or preventing the harmful effects of solar radiation on skin. Also disclosed are novel sunscreen compositions comprising 3-[2-(4-diethylaminophenyl)-2-oxoethyl]thiazolium salt for reducing or preventing the harmful effects of solar radiation on skin. Agents that provide UV-A and UV-B filters are also included. The invention further discloses additional sunscreen active agents, emollients, humectants, dry-feel modifiers, waterproofing agents, insect repellants, antimicrobial preservatives, antioxidants, chelating agents, fragrances and moisturizers, suitable carriers for topical application and emulsions.
1. A method of reducing or preventing harmful effects of solar radiation on skin comprising, applying a composition, comprising an effective amount of 3-[2-(4-diethylaminophenyl)-2-oxoethyl]thiazolium salt.
2. The method of claim 1 , wherein the effective amount of 3-[2-(4-diethylaminophenyl)-2-oxoethyl]thiazolium salt is between about 0.5% and about 10% by weight of the composition.
3. The method of claim 1 , wherein the composition further comprises a suitable carrier for topical application to human skin.
4. The method of claim 1 , wherein the composition further comprises one or more agents that provide a UV-B filter.
5. The method of claim 4 , wherein the one or more agents that provide a UV-B filter are selected from the group consisting of paramethoxycinnamic acid esters and octyl salicylate.
6. The method of claim 1 , wherein the composition further comprises one or more agents that provide a UV-A filter.
7. The method of claim 6 , wherein the one or more agents that provide a UV-A filter are selected from the group consisting of dibenzoylmethane derivatives, 4-(1,1-dimethylethyl)-4′-methoxydibenzoylmethane, and 4-isopropyl dibenzoylmethane.
8. The method of claim 1 , wherein the composition further comprises one or more agents that provide a UV-A filter and one or more agents that provide a UV-B filter.
9. A sunscreen composition for the reduction or prevention of harmful effects of solar radiation on skin comprising an effective amount of 3-[2-(4-diethylaminophenyl)-2-oxoethyl]thiazolium salt and a suitable carrier for application to the skin.
10. The composition of claim 9 , wherein the effective amount of 3-[2-(4-diethylaminophenyl)-2-oxoethyl]thiazolium salt is between about 0.5% and about 10% by weight of the composition.
11. The composition of claim 9 , wherein the composition further comprises one or more agents that provide a UV-B filter.
12. The composition of claim 11 , wherein the one or more agents that provide a UV-B filter are selected from the group consisting of paramethoxycinnamic acid esters and octyl salicylate.
13. The composition of claim 9 , wherein the composition further comprises one or more agents that provide a UV-A filter.
14. The composition of claim 13 , wherein the one or more agents that provide a UV-A filter are selected from the group consisting of dibenzoylmethane derivatives, 4-(1,1-dimethylethyl)-4′-methoxydibenzoylmethane, and 4-isopropyl dibenzoylmethane.
15. The composition of claim 9 , wherein the composition further comprises one or more agents that provide a UV-A filter and one or more agents that provide a UV-B filter.
16. The composition of claim 9 , wherein the composition further comprises one or more sunscreen active agents, wherein the one or more sunscreen active agents are selected from the group consisting of para aminobenzoic acid, avobenzone, cinoxate, dioxybenzone, homosalate, menthyl anthranilate, octocrylene, octyl methoxycinnamate, oxybenzone, padimate O, phenylbenzimidazole sulfonic acid, sulisobenzone, trolamine salicylate, titanium dioxide, zinc oxide, diethanolamine methoxycinnamate, digalloy trioleate, ethyl dihydroxypropyl PABA, glyceryl aminobenzoate, lawsone with dihydroxyacetone, red petrolatum, homomenthyl salicylate, Benzophenone-3, Uvinul MS-40, Uvasorb MET/C, and Neo Heliopan 303 or mixtures thereof.
17. The composition of claim 9 , wherein the composition further comprises one or more components selected from the group consisting of emollients, humectants, dry-feel modifiers, waterproofing agents, insect repellants, antimicrobial preservatives, antioxidants, chelating agents, fragrances and moisturizers.
18. The composition of claim 9 , wherein the composition is in the form of an emulsion.
19. The emulsion of claim 18 , further comprising a hydrophobic component that imparts film-forming and waterproofing characteristics to the emulsion.
20. The emulsion of claim 19 , wherein the hydrophobic component is a polymer selected from the group consisting of a copolymer comprising octadecene-1 and maleic anhydride monomers, polyanhydride resin and a copolymer comprising vinyl pyrollidone and eicosene monomers.