IP Library Granted Patent US 7,267,658
Granted Patent B2
US 7,267,658 · App. 10/808,213 · Granted Sep 11, 2007

Renal replacement therapy device for controlling fluid balance of treated patient

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 7,267,658
App. No.
10/808,213
Granted
Sep 11, 2007
Kind
B2
Abstract

A first flow path is defined within a first panel that forms a part of an extracorporeal fluid circuit. A second flow path is defined within a second panel that also forms a part of the extracorporeal fluid circuit. The first and second panels are oriented in a fluid processing cartridge for mounting as an integrated unit on a fluid processing machine and for removal as an integrated unit from the fluid processing machine.

Claims (5)

1. A fluid replacement system, comprising: blood treatment apparatus that generates outgoing fluid and consumes ingoing fluid; a chamber including an interior wall dividing the chamber into a first compartment to retain a volume of outgoing fluid and a second compartment to retain a volume of ingoing fluid, the interior wall responding to differential fluid pressure to displace outgoing fluid from the first compartment as ingoing fluid is conveyed into the second compartment and vice versa, an outgoing line to conduct outgoing fluid, a first pump assembly communicating with the outgoing line and the first compartment, a second pump assembly communicating with a source of ingoing fluid and the second compartment, a third pump assembly communicating with the outgoing line and the first compartment at a location upstream of the first pump assembly, and a controller coupled to the first, second, and third pump assemblies, being operable in a first cycle, during which the first and second pump assemblies are operated to convey a volume of outgoing fluid into the first compartment to displace a volume of ingoing fluid from the second compartment, the controller also being operable in a second cycle, during which the first and second pump assemblies are operated to convey a volume of ingoing fluid into the second compartment to displace a volume of outgoing fluid from the first compartment, the controller being selectively operable during the first and second cycles to operate the third pump assembly in a bolus mode, during which a volume of outgoing fluid is recirculated from the first compartment into the outgoing line to displace ingoing fluid from the second compartment while limiting removal of additional outgoing fluid by the blood treatment apparatus.

2. A system according to claim 1 , wherein the controller is selectively operable to operate the third pump assembly in an ultrafiltration mode, during which outgoing fluid is conveyed from the outgoing line in a path that bypasses the first pump assembly.

3. A system according to claim 2 , wherein the controller is operable in the ultrafiltration mode during the first and second cycles.

4. A system according to claim 1 , wherein the controller operates during the first and second cycles to achieve a predetermined volumetric balance between waste fluid conveyed into the first compartment and replacement fluid conveyed from the second compartment, and vice versa.

5. A system according to claim 1 , wherein the controller is operable to maintain prescribed pump rates for the first, second, and third pump assemblies, and wherein, during the bolus mode, the pump rate prescribed for the third pump assembly is less than the pump rate prescribed for either the first pump assembly or the second pump assembly.

Assignments (9)
RELEASE OF SECURITY INTEREST Recorded Feb 21, 2019
From: CAPITAL ONE, NATIONAL ASSOCIATION (AS SUCCESSOR BY MERGER TO HEALTHCARE FINANCIAL SOLUTIONS, LLC)
To: NXSTAGE MEDICAL, INC.
Reel/Frame 048407/0865 →
RELEASE OF SECURITY INTEREST Recorded Jul 28, 2017
From: ASAHI KASEI MEDICAL CO., LTD. F/K/A ASAHI KASEI KURARAY MEDICAL CO., LTD.
To: NXSTAGE MEDICAL, INC.; MEDISYSTEMS CORPORATION; MEDISYSTEMS SERVICES CORPORATION
Reel/Frame 043364/0936 →
ASSIGNMENT OF INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Nov 16, 2015
From: GENERAL ELECTRIC CAPITAL CORPORATION, AS RETIRING AGENT
To: HEALTHCARE FINANCIAL SOLUTIONS, LLC, AS SUCCESSOR AGENT
Reel/Frame 037112/0376 →
RELEASE OF SECURITY INTEREST Recorded Jun 11, 2014
From: SILICON VALLEY BANK
To: NXSTAGE MEDICAL, INC.
Reel/Frame 033133/0902 →
SECURITY INTEREST Recorded Jun 10, 2014
From: NXSTAGE MEDICAL, INC.
To: GENERAL ELECTRIC CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT
Reel/Frame 033123/0836 →
SECURITY AGREEMENT Recorded Mar 22, 2010
From: NXSTAGE MEDICAL, INC.
To: SILICON VALLEY BANK
Reel/Frame 024114/0789 →
RELEASE OF SECURITY INTEREST Recorded Jun 10, 2009
From: GE BUSINESS FINANCIAL SERVICES INC.
To: NXSTAGE MEDICAL, INC.; EIR MEDICAL, INC.; MEDISYSTEMS CORPORATION; MEDISYSTEMS SERVICES CORPORATION
Reel/Frame 022804/0150 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Jun 10, 2009
From: NXSTAGE MEDICAL, INC.; EIR MEDICAL, INC.; MEDISYSTEMS CORPORATION; MEDISYSTEMS SERVICES CORPORATION
To: ASAHI KASEI KURARAY MEDICAL CO., LTD.
Reel/Frame 022804/0496 →
SECURITY AGREEMENT Recorded Apr 7, 2009
From: NXSTAGE MEDICAL, INC.; EIR MEDICAL, INC.; MEDISYSTEMS CORPORATION; MEDISYSTEMS SERVICES CORPORATION
To: GE BUSINESS FINANCIAL SERVICES INC.
Reel/Frame 022610/0602 →