IP Library Granted Patent US 7,205,290
Granted Patent B2
US 7,205,290 · App. 10/813,954 · Granted Apr 17, 2007

Diphenylazetidinone with improved physiological properties, process for its preparation, medicaments comprising this compound, and its use

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Quick Facts
Patent No.
US 7,205,290
App. No.
10/813,954
Granted
Apr 17, 2007
Kind
B2
Abstract

The invention relates to the compound of the formula 1 and to its physiologically acceptable salts. The compound is suitable, for example, as a hypolipidemic.

Claims (9)

1. A compound of the formula I

or pharmaceutically acceptable salts thereof.

2. A pharmaceutical composition comprising a pharmaceutically acceptable carrier and the compound of claim 1 .

3. A method of treating hyperlipidemia comprising administering to a patient in need thereof a therapeutically effective amount of a compound of claim 1 .

4. A method of lowering serum cholesterol concentration comprising administering to a patient in need thereof a therapeutically effective amount of a compound of claim 1 .

5. A method of treating arteriosclerotic symptoms comprising administering to a patient in need thereof a therapeutically effective amount of a compound of claim 1 .

6. A method of treating insulin resistance comprising administering to a patient in need thereof a therapeutically effective amount of a compound of claim 1 .

7. An intermediate of the formula IV

in which R is acetyl, benzoyl, aryl (C 1 –C 12 )-alkylaryl or (C 1 –C 12 )-alkyl.

Assignments (2)
CHANGE OF NAME Recorded Nov 18, 2005
From: AVENTIS PHARMA DEUTSCHLAND GMBH
To: SANOFI-AVENTIS DEUTSCHLAND GMBH
Reel/Frame 016793/0789 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 12, 2004
From: JAEHNE, DR. GERHARD; FRICK, DR. WENDELIN; LINDENSCHMIDT, DR. ANDREAS; FLOHR, DR. STEFANIE; HEUER, DR. HUBERT; SCHAEFER, DR. HANS-LUDWIG; KRAMER, DR. WERNER; GALIA, DR. ERIC; GLOMBIK, DR. HEINER
To: AVENTIS PHARMA DEUTSCHLAND GMBH
Reel/Frame 015241/0672 →