Wound and ulcer treatment with super-oxidized water
View Patent ↗Super-oxidized water based on hypochlorous acid, such as is obtained by the electrochemical treatment of a saline solution, may be used in the treatment of leg ulcers or other open wounds. Preferably, the pH of the super-oxidized water is in a range of 4 to 7, and the water has a redox potential of >950 mV. Medicaments based on the super-oxidized water may be in liquid or gel form. The super-oxidized water is able to control the microbial population within the wound and at the same time permit cell proliferation.
1. A method for treating an open wound in a human or animal body comprising administering to the open wound an output solution comprising hypochlorous acid,
said output solution: having a pH of 4 to 7, a redox potential of >950 mV, and being obtained by electrochemical treatment of a saline solution; and
wherein the output solution is administered in an amount effective to act as a biocide and permit cell proliferation for wound healing.
2. The method according to claim 1 , wherein the open wound is an ulcer, burn, or surface wound.
3. The method according to claim 1 , wherein the output solution is in a liquid form and is applied to the wound by bathing.
4. The method according to claim 3 , wherein the output solution is applied to the wound by immersion in a hydrobath containing the output solution.
5. The method according to claim 1 , wherein the output solution is in a liquid form and is applied to the wound by spraying.
6. The method according to claim 1 , wherein the output solution is in a gel form and is topically applied to the wound.
7. The method according to claim 1 , wherein the output solution has a pH of 4.0 to 6.5.
8. The method according to claim 7 , wherein the output solution has a pH of 4.0 to 6.2.
9. The method according to claim 8 , wherein the output solution has a pH of 4.3 to 6.2.
10. The method according to claim 9 , wherein the output solution has a pH of about 5.4.
11. The method according to claim 1 , wherein the output solution has a redox potential of about 1000 mV.
12. The method according to claim 1 , wherein the output solution, or a preparation derived therefrom, has a biocide rate (D Value) of approximately 1 log reduction unit bacillus subtilis spores in less than 1 minute with a 9:1 output solution: innoculum mix.
13. The method according to claim 1 , wherein the output solution is diluted.
14. The method according to claim 13 , wherein the output solution is diluted to an extent that it promotes cell proliferation.
15. The method according to claim 1 , wherein the output solution has a pH adjusted to a desired level by using an alkaline solution output from an electrochemical cell in which the saline solution is treated.
16. The method according to claim 1 , wherein the output solution further comprises a phosphate buffer to adjust a pH of the solution to a desired level.
17. The method according to claim 1 , wherein the output solution has an available free chlorine concentration of about 144 mg/l to 400 mg/l.
18. A method for treating an open wound in a mammal comprising administering to the open wound an output solution obtained by electrochemical treatment of a saline solution, the output solution comprising hypochlorous acid, having an available free chlorine concentration of about 144 mg/l to 400 mg/l, and having a pH of 4 to 7, wherein the output solution is administered in an amount effective to act as a biocide and permit cell proliferation for wound healing.
19. The method according to claim 18 , wherein the open wound is an ulcer, burn, or surface wound.
20. The method according to claim 18 , wherein the output solution is in a liquid form and is applied to the wound by bathing.
21. The method according to claim 18 , wherein the output solution is applied to the wound by immersion in a hydrobath containing the output solution.
22. The method according to claim 18 , wherein the output solution is in a liquid form and is applied to the wound by spraying.
23. The method according to claim 18 , wherein the output solution is in a gel form and is topically applied to the wound.
24. The method according to claim 18 , wherein the output solution has a pH of 4.0 to 6.5.
25. The method according to claim 18 , wherein the output solution has a pH of 4.0 to 6.2.
26. The method according to claim 18 , wherein the output solution has a pH of 4.3 to 6.2.
27. The method according to claim 18 , wherein the output solution has a pH of about 5.4.
28. The method according to claim 18 , wherein the output solution has a redox potential of >950 mV.
29. The method according to claim 18 , wherein the output solution has a redox potential of about 1000 mV.
30. The method according to claim 18 , wherein the output solution, or a preparation derived therefrom, has a biocide rate (D Value) of approximately 1 log reduction unit bacillus subtilis spores in less than 1 minute with a 9:1 output solution: innoculum mix.
31. The method according to claim 18 , wherein the output solution is diluted.
32. The method according to claim 18 , wherein the output solution is diluted to an extent that it promotes cell proliferation.
33. The method according to claim 18 , wherein the output solution has a pH adjusted to a desired level by using an alkaline solution output from an electrochemical cell in which the saline solution is treated.
34. The method according to claim 18 , wherein the output solution further comprises a phosphate buffer to adjust a pH of the solution to a desired level.