Target molecules detection by waveguiding in a photonic silicon membrane
View Patent ↗Disclosed herein is a porous silicon filter capable of binding and detecting biological and chemical target molecules in liquid or gas samples. A photonic waveguiding silicon filter with chemical and/or biological anchors covalently attached to the pore walls bind target molecules. The system uses transmission curve engineering principles to allow measurements to be made in situ and in real time to detect the presence of various target molecules and calculate the concentration of bound target.
1. A photonic waveguiding device comprising:
at least one silicon wafer having a plurality of through pores, wherein said pores are distributed according to a designed pattern leading to a photonic band gap; and
at least one chemical or biological target specific anchor attached to the inner wall of at least one of said pores, wherein said anchor is attached to said pore wall via silicon-carbon covalent bonding.
2. The photonic waveguiding device recited in claim 1 , wherein said pores have pore diameters ranging in size from about 100 nm to about 1 μm.
3. The photonic waveguiding device recited in claim 1 , wherein the total size of said device has dimensions no larger than 200 μm×1 cm×1 cm.