IP Library Granted Patent US 7,341,078
Granted Patent B1
US 7,341,078 · App. 10/841,327 · Granted Mar 11, 2008

Automatic container bulk filling process

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Quick Facts
Patent No.
US 7,341,078
App. No.
10/841,327
Granted
Mar 11, 2008
Kind
B1
Abstract

An automatic bulk filling process for filling a large number of liquid containers ( 20 ) simultaneously which consists of placing the open-topped liquid containers upside down in a rack ( 22 ). The rack is then inserted into a vacuum chamber ( 28 ) and positioned directly above a tray ( 38 ) that contains a liquid medicinal product ( 40 ). The next step is to evacuate the chamber to a predetermined level below atmospheric pressure and then lowering the rack until the containers are partially immersed in the liquid product. Following that step, nitrogen is introduced into the vacuum chamber at a predetermined gradual rate, thereby quickly forcing the medicinal liquid product into the containers. The rack is then raised from the tray containing the liquid medicinal product and removed from the chamber as another rack full of containers is simultaneously inserted into the chamber from the other end.

Claims (20)

1. An automatic bulk filling process for simultaneously filling liquid containers which comprises the steps of:

a) placing a plurality of open-topped liquid containers upside down in a rack,

b) inserting said rack into a vacuum chamber,

c) positioning said rack directly above a tray containing a liquid medicinal product,

d) evacuating said vacuum chamber to a predetermined level below atmospheric pressure,

e) reducing the pressure within said vacuum chamber with a first vacuum pump and a second vacuum pump with each having a different capacity, and two buffer tanks with each having an inlet valve and an outlet valve for quickly reaching the desired vacuum level of the process,

f) lowering said rack until said containers are partially immersed in said liquid product,

g) introducing nitrogen into said vacuum chamber at a predetermined gradual rate, thereby forcing said medicinal liquid product into said containers,

h) raising said rack from said tray containing said liquid medicinal product, and

i) removing said rack with filled containers as another rack full of containers is simultaneously inserted into said vacuum chamber.

2. An automatic bulk filling process for simultaneously filling liquid containers which comprises the steps of:

a) placing a plurality of open-topped liquid containers upside down in a rack,

b) inserting said rack into a vacuum chamber,

c) positioning said rack directly above a tray containing a liquid medicinal product,

d) evacuating said vacuum chamber to a predetermined level below atmospheric pressure,

e) reducing the pressure within said vacuum chamber with a first vacuum pump and a second vacuum pump with each having a different capacity, and two buffer tanks with each having an inlet valve and an outlet valve for quickly reaching the desired vacuum level of the process, wherein said first vacuum pump and said second vacuum pump further comprise the step of reducing the pressure, with the first vacuum pump capable of rapidly reaching a rough/low vacuum level and said second pump capable of reaching a high vacuum,

f) lowering said rack until said containers are partially immersed in said liquid product,

g) introducing nitrogen into said vacuum chamber at a predetermined gradual rate, thereby forcing said medicinal liquid product into said containers,

h) raising said rack from said tray containing said liquid medicinal product, and

i) removing said rack with filled containers as another rack full of containers is simultaneously inserted into said vacuum chamber.

Assignments (4)
SECURITY INTEREST Recorded Jun 30, 2023
From: AMPHASTAR PHARMACEUTICALS, INC.
To: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT
Reel/Frame 064124/0933 →
RELEASE OF SECURITY INTEREST Recorded Jun 29, 2023
From: CAPITAL ONE, NATIONAL ASSOCIATION, AS AGENT
To: ARMSTRONG PHARMACEUTICALS, INC.; INTERNATIONAL MEDICATION SYSTEMS, LIMITED
Reel/Frame 064119/0605 →
SECURITY INTEREST Recorded Aug 4, 2021
From: AMPHASTAR PHARMACEUTICALS, INC.; INTERNATIONAL MEDICATION SYSTEMS, LIMITED; ARMSTRONG PHARMACEUTICALS, INC.
To: CAPITAL ONE, NATIONAL ASSOCIATION
Reel/Frame 057086/0313 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 14, 2005
From: XIA, FRANK SHI SHI; LOU, ZHI DONG; ZHANG, JACK YOUNG FENG; LUO, MARY ZI PING
To: AMPHASTAR PHARMACEUTICALS, INC.
Reel/Frame 016858/0217 →