Mask configured to maintain nutrient transport without producing visible diffraction patterns

1. An implantable mask for treating presbyopia, comprising:

an anterior surface extending between an outer periphery and a central optical axis of the mask, the anterior surface configured to reside adjacent a first layer of the stroma of a cornea;

a posterior surface extending between the outer periphery and the central optical axis of the mask, the posterior surface configured to reside adjacent a second layer of the stroma of the cornea;

a mask thickness between the anterior and posterior surfaces of less than about 20 microns;

a substantially opaque portion extending between the anterior and posterior surfaces and between the outer periphery and the central optical axis, the opaque portion comprising an inner region, an outer region, and a central region disposed between the inner and outer regions, the opaque portion configured to prevent transmission of light;

an aperture disposed about the central optical axis and configured to transmit substantially all incident light, the aperture having a dimension generally transverse to the optical axis, the dimension being about 2.2 millimeters or less;

a plurality of transport holes having a hole entrance at the anterior surface and extending from the anterior surface to the posterior surface, the hole entrances providing an open area of the mask such that sufficient transport of tissue maintaining substances through the mask between the first and second stromal layers is enabled to prevent depletion of tissue maintaining substances that would harm adjacent stromal layers;

wherein the holes are positioned at irregular locations between the inner region and the outer region to minimize the generation of visible artifacts due to the transmission of light through the holes; and

wherein the inner region and outer region are devoid of open area.

2. The mask of claim 1 , wherein each of the holes extends along a length between the posterior surface and the anterior surface and has a substantially constant cross-sectional shape along the length, wherein the cross-sectional shape of a substantial number of the plurality of holes is non-uniform.

3. The mask of claim 2 , wherein a substantial number of the holes comprise an elongate opening located at the anterior surface of the mask, each opening having a major axis and a minor axis generally transverse to the major axis, wherein a substantial number of the major axes have a non-uniform orientation.

4. The mask of claim 1 , wherein a substantial number of the holes comprise an elongate opening located at the anterior surface of the mask, each opening having a major axis and a minor axis generally transverse to the major axis, wherein a substantial number of the major axes have a non-uniform orientation.

5. The mask of claim 1 , wherein at least one of the holes generates a wavefront that is substantially destructively interfered with by a wavefront generated by another hole.

6. The mask of claim 1 , wherein a first hole is configured to generate a first wavefront of light and a second hole is configured to generate a second wavefront of light such that the first wavefront is destructively interfered with by the second wavefront.

7. The mask of claim 1 , wherein the holes are configured to minimize depletion of glucose.

8. The mask of claim 1 , wherein a thickness of between about 5 microns and about 10 microns is defined between the anterior and posterior surfaces.

9. The mask of claim 1 , wherein a thickness of about 5 microns is defined between the anterior and posterior surfaces.

10. The mask of claim 1 , wherein the holes extend posteriorly from a hole entrance on the anterior surface, a total surface area of the hole entrances comprising about 5 percent or more of a total surface area of the anterior surface.

11. The mask of claim 1 , wherein the hole entrances have a transverse dimension at the anterior surface of between about 20 and about 29 microns.

12. The mask of claim 1 , wherein each of the irregular locations is separated from each adjacent irregular location by minimum amount.

13. The mask of claim 12 , wherein the minimum amount of separation between adjacent holes is about 20 microns.

14. The mask of claim 1 , wherein the inner region extends radially outwardly from an inner periphery by about 0.050 mm.

15. The mask of claim 1 , wherein the outer region extends radially inwardly from the outer periphery by about 0.050 mm.

16. The mask of claim 15 , wherein the inner region extends radially outwardly from an inner periphery by about 0.050 mm.

17. The mask of claim 15 , wherein the hole entrances have a transverse dimension of at least about 15 microns.

18. The mask of claim 1 , wherein the inner region comprises an annular band that extends from the aperture to an inner portion of the central region.

19. The mask of claim 1 , wherein the outer region comprises an annular band that extends from the outer periphery to an outer portion of the central region.

20. The mask of claim 19 , wherein the inner region comprises an annular band that extends from the aperture to an inner portion of the central region.