Granted Patent
B2
US 7,989,490 · App. 10/858,954 · Granted Aug 2, 2011
Injectable formulations of taxanes for cad treatment
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Abstract
Liquid formulations, including solutions and suspensions of the various drugs, agents and/or compounds, may be locally or regionally delivered for the treatment of vascular disease. In each of these instances, antioxidants are utilized to prolong product integrity.
Claims (6)
1. An aqueous formulation of a therapeutic agent comprising:
paclitaxel in a concentration of 1.25 mg/ml;
3.75 percent vitamin E d-alpha tocopheryl polyethylene glycol succinate (Vitamin E TPGS);
0.5 percent ethanol;
25 percent poly(ethylene glycol) 400; and
70 percent water, the aqueous formulation comprising a stable solution for at least one of direct local or regional delivery into arterial tissue.
Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Oct 1, 2025
From: CARDINAL HEALTH SWITZERLAND 515 GMBH; CARDINAL HEALTH 529, LLC; CORDIS CORPORATION; FLEXIBLE STENTING SOLUTIONS, INC
To: CORDIS US CORP
Reel/Frame 072987/0675 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Mar 31, 2017
From: CORDIS CORPORATION
To: CARDINAL HEALTH SWITZERLAND 515 GMBH
Reel/Frame 042126/0259 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 19, 2004
From: FALOTICO, ROBERT; ZHAO, JONATHON Z.
To: CORDIS CORPORATION
Reel/Frame 015690/0953 →