IP Library › Granted Patent US 7,361,491
Granted Patent B2
US 7,361,491 · App. 10/859,792 · Granted Apr 22, 2008

DNA molecules encoding human NHL, a DNA helicase

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 7,361,491
App. No.
10/859,792
Granted
Apr 22, 2008
Kind
B2
Abstract

The present invention disclosed isolated nucleic acid molecules (polynucleotides) which encode NHL, a putative DNA helicase. The present invention in turn relates to recombinant vectors and recombinant hosts which contain a DNA fragment encoding NHL, substantially purified forms of associated NHL, associated mutant proteins, and methods associated with identifying compounds which modulate NHL, which will be useful in the treatment of various neoplastic disorders. Both a genomic clone containing regulatory and intron sequences, as well as the exon structure and open reading frame of human NHL are disclosed.

Claims (2)

1. A substantially purified human helicase protein which comprises the amino acid sequence as set forth in SEQ ID NO:2.

2. A substantially purified human helicase protein which consists of the amino acid sequence as set forth in SEQ ID NO:2.

Assignments (1)
CHANGE OF NAME Recorded Jan 29, 2010
From: MERCK & CO., INC.
To: MERCK SHARP & DOHME CORP.
Reel/Frame 023861/0910 →