Systems, methods and apparatuses for manufacturing dosage forms
View Patent ↗Systems, methods and apparatuses for manufacturing dosage forms, and to dosage forms made using such systems, methods and apparatuses are provided. Novel compression, thermal cycle molding, and thermal setting molding modules are disclosed. One or more of such modules may be linked, preferably via novel transfer device, into an overall system for making dosage forms.
1. A method for making an insert, comprising the steps of:
a) injecting a starting material in flowable form comprising a medicant and a thermal setting material into a molding chamber having a shape;
b) solidifying said starting material so as to form a solid insert having the shape of said molding chamber wherein, said molding chamber comprises a piston disposed therein, said piston being capable of displacement within said molding chamber; and
c) ejecting said solid insert from said molding chamber by displacing said piston within said molding chamber, wherein said steps occur during rotation of said molding chambers about a central axis, and
wherein said method further comprises the step of adjusting the volume of said molding chamber by displacing said piston therein.
2. Product made by the process of claim 1 .
3. The method according to claim 1 , further comprising the steps of:
d) embedding said solid insert into a powder comprising a second medicant; and
e) compressing said powder around said insert.
4. The method according to claim 1 , wherein said starting material is above room temperature when injected into said molding chamber, and wherein solidifying step (b) comprises cooling said mixture.
5. The method according to claim 1 , wherein said injecting step (a) comprises placing a nozzle adjacent said molding chamber and delivering said starting material directly from said nozzle into said molding chamber.