IP Library › Patent Application 10884852
Patent Application
App. No. 10/884,852

Immunostimulatory nucleic acid molecules

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Patent No.
US None
App. No.
10/884,852
Abstract

Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.

Claims (3)

1 - 18 . (Cancelled)

19 . A method for blocking apoptosis in a murine or human cell comprising contacting the murine or human cell with an immunostimulatory oligonucleotide.

20 . The method of claim 19 , wherein the immunostimulatory oligonucleotide is a CpG oligonucleotide.

Assignments (9)
CONFIRMATORY LICENSE Recorded Oct 10, 2008
From: UNIVERSITY OF IOWA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 021670/0841 →
CONFIRMATION OF EXCLUSIVE PATENT LICENSE Recorded Dec 20, 2005
From: COLEY PHARMACEUTICAL GROUP, INC.; COLEY PHARMACEUTICAL GROUP, LTD.; COLEY PHARMACEUTICAL, GMBH
To: PFIZER INC.
Reel/Frame 017353/0372 →
CORRECTIVE ASSIGNMENT TO CORRECT THE NAME OF THE A Recorded Jan 5, 2005
From: KLINMAN, DENNIS
To: UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, THE
Reel/Frame 015544/0173 →
CHANGE OF NAME Recorded Jan 5, 2005
From: CPG IMMUNOPHARMACEUTICALS, INC.
To: COLEY PHARMACEUTICAL GROUP, INC.
Reel/Frame 015544/0004 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 31, 2004
From: KLINE, JOEL
To: UNIVERSITY OF IOWA RESEARCH FOUNDATION, THE
Reel/Frame 015117/0440 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 9, 2004
From: KLINMAN, DENNIS
To: UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
Reel/Frame 015057/0252 →
CHANGE OF NAME Recorded Aug 9, 2004
From: CPG IMMUNOPHARMACEUTICALS, INC.
To: COLEY PHARMACEUTICALS GROUP INC.
Reel/Frame 015057/0277 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 9, 2004
From: KRIEG, ARTHUR M.
To: UNIVERSITY OF IOWA RESEARCH FOUNDATION, THE
Reel/Frame 014994/0081 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 9, 2004
From: STEINBERG, ALFRED D.
To: CPG IMMUNOPHARMACEUTICALS, INC.
Reel/Frame 014994/0091 →