Substituted benzoylureido-o-benzoylamides, process for their preparation and their use
View Patent ↗The invention relates to substituted benzoylureido-o-benzoylamides and to their physiologically tolerated salts and physiologically functional derivatives. The invention relates to compounds of the formula I in which the radicals have the stated meanings, and to the physiologically tolerated salts thereof. The compounds are suitable for example as medicaments for the prevention and treatment of type 2 diabetes.
1. A compound of the formula I,
wherein
R1, R2 are H;
R3, R4, R5, R6 are H;
R7 is H or (C 1 -C 6 )-alkyl;
R8, R9 are each, independently of one another, F or Cl;
R10, R11 are each, independently of one another, H, F, or Cl;
R12, R13 are each, independently of one another, H or F; or
R12 and R13 form together, with the carbon atom or the carbon atoms to which they are bonded, a 5- or 6-membered, saturated ring;
m is 1, 2, or 3; or and pharmaceutically acceptable salts thereof.
2. A pharmaceutical composition comprising one or more compounds of claim 1 and a pharmaceutically acceptable carrier.