Isoindoline compounds and methods of making and using the same
The invention encompasses isoindoline compounds, pharmaceutical compositions comprising them, and methods of their use for the treatment, prevention or management of various diseases and disorders. Examples include, but are not limited to, cancer, inflammatory bowel disease and myelodysplastic syndrome.
1. A pharmaceutical composition comprising a compound, or a pharmaceutically acceptable salt, solvate, or stereoisomer thereof, wherein the compound is:
2. The pharmaceutical composition of claim 1 , which further comprises a pharmaceutically acceptable carrier or excipient.
3. A dosage form comprising a compound, or a pharmaceutically acceptable salt, solvate, or stereoisomer thereof, wherein the compound is:
4. The dosage form of claim 3 , which is suitable for oral or parenteral administration.
5. The pharmaceutical composition of claim 1 , wherein the solvate is hydrate.
6. The dosage form of claim 3 , wherein the solvate is hydrate.