IP Library › Granted Patent US 6,998,406
Granted Patent B2
US 6,998,406 · App. 10/914,744 · Granted Feb 14, 2006

Fluorenecarboxylic acid esters, process for the manufacture thereof, and use thereof as medicaments

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Quick Facts
Patent No.
US 6,998,406
App. No.
10/914,744
Granted
Feb 14, 2006
Kind
B2
Abstract

Fluorenecarboxylic acid esters of general formula 1 wherein X − and the groups A, R, R 1 , R 2 , R 3 , R 3′ , R 4 , and R 4′ have the meanings given in the claims and in the specification, processes for the manufacture thereof and the use thereof as medicaments.

Claims (12)

1. Tropenol 9-hydroxyfluorene-9-carboxylate methobromide or a physiologically acceptable salt thereof.

2. Tropenol 9-fluorofluorene-9-carboxylate methobromide or an acid addition salt thereof.

3. Scopine 9-hydroxyfluorene-9-carboxylate methobromide or an acid addition salt thereof.

4. Scopine 9-fluorofluorene-9-carboxylate methobromide or an acid addition salt thereof.

5. A pharmaceutical composition comprising a compound according to claim 1 or a physiologically acceptable salt thereof and a pharmaceutically acceptable excipient or carrier.

6. A pharmaceutical composition comprising a compound according to claim 2 or a physiologically acceptable salt thereof and a pharmaceutically acceptable excipient or carrier.

7. A pharmaceutical composition comprising a compound according to claim 3 or a physiologically acceptable salt thereof and a pharmaceutically acceptable excipient or carrier.

8. A pharmaceutical composition comprising a compound according to claim 4 or a physiologically acceptable salt thereof and a pharmaceutically acceptable excipient or carrier.

9. A method for treatment of asthma or COPD in a patient, the method comprising administering to the patient in need thereof an effective amount of a compound according to claim 1 .

10. A method for treatment of asthma or COPD in a patient, the method comprising administering to the patient in need thereof an effective amount of a compound according to claim 2 .

11. A method for treatment of asthma or COPD in a patient the method comprising administering to the patient in need thereof an effective amount of a compound according to claim 3 .

12. A method for treatment of asthma or COPD in a patient, the method comprising administering to the patient in need thereof an effective amount of a compound according to claim 4 .