IP Library › Granted Patent US 7,425,612
Granted Patent B2
US 7,425,612 · App. 10/916,064 · Granted Sep 16, 2008

Genes and polypeptides relating to human colon cancers

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Quick Facts
Patent No.
US 7,425,612
App. No.
10/916,064
Granted
Sep 16, 2008
Kind
B2
Abstract

The present application provides novel human genes RNF43 whose expression is markedly elevated in colorectal cancers, as well as CXADRL1 and GCUD1 whose expression is markedly elevated in gastric cancers compared to corresponding non-cancerous tissues. The genes and polypeptides encoded by the genes can be used, for example, in the diagnosis of a cell proliferative disease, and as target molecules for developing drugs against the disease.

Claims (4)

1. An isolated polypeptide comprising the amino acid sequence of SEQ ID NO:6.

2. An isolated polypeptide consisting of the amino acid sequence of SEQ ID NO:80.

3. An isolated polypeptide consisting of the amino acid sequence of SEQ ID NO:97.

4. An isolated polypeptide consisting of the amino acid sequence of SEQ ID NO:108.

Assignments (4)
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE'S NAME FROM ONCOTHERAPHY SCIENCE, INC. TO ONCOTHERAPY SCIENCE, INC. PREVIOUSLY RECORDED ON REEL 018669 FRAME 0205. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT OF ASSIGNOR'S INTEREST. Recorded Feb 5, 2007
From: THE UNIVERSITY OF TOKYO
To: ONCOTHERAPY SCIENCE, INC.
Reel/Frame 018853/0223 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 21, 2006
From: THE UNIVERSITY OF TOKYO
To: ONCOTHERAPHY SCIENCE, INC.
Reel/Frame 018669/0205 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEES' ADDRESSES TO INSERT "TOKYO" AS THE CITY PREVIOUSLY RECORDED ON REEL 015423 FRAME 0281. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jun 13, 2005
From: NAKAMURA, YUSUKE; FURUKAWA, YOICHI; TAHARA, HIDEAKI; TSUNODA, TAKUYA
To: THE UNIVERSITY OF TOKYO; ONCOTHERAPY SCIENCE, INC.
Reel/Frame 016132/0613 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 7, 2004
From: NAKAMURA, YUSUKE; FURUKAWA, YOICHI; TAHARA, HIDEAKI; TSUNODA, TAKUYA
To: THE UNIVERSITY OF TOKYO; ONCOTHERAPY SCIENCE, INC.
Reel/Frame 015423/0281 →