IP Library Granted Patent US 7,458,963
Granted Patent B2
US 7,458,963 · App. 10/923,109 · Granted Dec 2, 2008

Methods, systems, and kits for lung volume reduction

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Quick Facts
Patent No.
US 7,458,963
App. No.
10/923,109
Granted
Dec 2, 2008
Kind
B2
Abstract

Lung volume reduction is performed in a minimally invasive manner by isolating a lung tissue segment, optionally reducing gas flow obstructions within the segment, and aspirating the segment to cause the segment to at least partially collapse. Further optionally, external pressure may be applied on the segment to assist in complete collapse. Reduction of gas flow obstructions may be achieved in a variety of ways, including over inflation of the lung, introduction of mucolytic or dilation agents, application of vibrational energy, induction of absorption atelectasis, or the like. Optionally, diagnostic procedures on the isolated lung segment may be performed, typically using the same isolation/access catheter.

Claims (11)

1. A method of reducing lung size of a lung, the method including the steps of:

inserting a conduit down a trachea, into a mainstem bronchus, into a bronchial branch, and into a bronchial sub-branch communicating with a lung portion of the lung to be reduced in size;

pulling a vacuum in the lung portion through the conduit to collapse the lung portion; and

deploying an obstructing member in the bronchial sub-branch to preclude air from being inhaled into the lung portion through the bronchial sub-branch.

2. The method of claim 1 , wherein the deploying step includes feeding the obstructing member down the conduit and into the bronchial sub-branch.

3. A method for lung volume reduction, said method comprising:

isolating a lung tissue segment;

aspirating the isolated segment to cause the segment to collapse; and

sealing an air passage which opens to the lung segment to inhibit reinflation of the segment.

4. The method of claim 3 , wherein sealing comprises deploying a plug in the air passage.

5. The method of claim 4 , wherein deploying comprises advancing the plug through a catheter to the air passage.

Assignments (8)
RELEASE OF SECURITY INTEREST Recorded Mar 4, 2026
From: CANADIAN IMPERIAL BANK OF COMMERCE
To: PULMONX CORPORATION
Reel/Frame 075028/0274 →
RELEASE OF SECURITY INTEREST Recorded Sep 30, 2020
From: OXFORD FINANCE LLC, AS COLLATERAL AGENT
To: PULMONX CORPORATION
Reel/Frame 053952/0044 →
RELEASE OF SECURITY INTEREST Recorded Sep 30, 2020
From: BOSTON SCIENTIFIC CORPORATION
To: PULMONX CORPORATION
Reel/Frame 053953/0548 →
SECURITY INTEREST Recorded Mar 2, 2020
From: PULMONX CORPORATION
To: CANADIAN IMPERIAL BANK OF COMMERCE
Reel/Frame 052916/0213 →
MERGER Recorded Apr 23, 2019
From: PULMONX
To: PULMONX CORPORATION
Reel/Frame 048964/0563 →
SECURITY INTEREST Recorded Jul 26, 2017
From: PULMONX CORPORATION
To: BOSTON SCIENTIFIC CORPORATION
Reel/Frame 043349/0725 →
SECURITY INTEREST Recorded May 15, 2017
From: PULMONX CORPORATION
To: OXFORD FINANCE LLC, AS COLLATERAL AGENT
Reel/Frame 042466/0349 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 2, 2010
From: PERKINS, RODNEY C.; SOLTESZ, PETER P.; KOTMEL, ROBERT
To: PULMONX
Reel/Frame 023882/0092 →