Porous substrates, articles, systems and compositions comprising nanofibers and methods of their use and production
View Patent ↗Porous nanofiber bearing substrate materials are provided having enhanced surface area for a variety of applications including as electrical substrates, semipermeable membranes and barriers, structural lattices for tissue culturing and for composite materials, and the like.
1. A bandage, comprising:
a flexible porous substrate having a plurality of apertures disposed therethrough, the porous substrate having an overall surface that includes an interior wall surface of the apertures and an exterior surface of the substrate; and
a plurality of nanofibers deposited upon or attached to at least a portion of the overall surface of the porous substrate, wherein at least a portion of the nanofibers are attached to or deposited upon the exterior surface of the substrate and at least a portion of the nanofibers are attached to the interior wall surface area of the plurality of apertures, whereby when the bandage is applied to a wound, the nanofibers attached to the exterior surface of the substrate provide adhesion to surface tissues adjacent to the wound or to an opposing side of the substrate.
2. The bandage of claim 1 , comprising a protective pad disposed upon a first portion of a first side of the substrate, whereby when the bandage is applied to a wound, the protective pad overlays the wound.
3. The bandage of claim 1 , wherein the nanofibers are functionalized with a hydrophobic chemical moiety, and wherein the nanofibers and aperture together define a pore which is permeable to gas and not permeable to water.
4. The bandage of claim 1 , wherein the nanofibers are grown in situ on the substrate material.
5. The bandage of claim 1 , wherein at least a portion of the nanofibers are oriented in a direction extending away from the surface of the substrate at the point of attachment between the nanofibers and the substrate.
6. The bandage of claim 1 , wherein the nanofibers comprise an inorganic semiconductor, an inorganic semiconductor oxide, a ceramic, or a biologically derived compound, or are carbon nanotubes.
7. The bandage of claim 1 , wherein the nanofibers comprise silicon.
8. The bandage of claim 1 , wherein the nanofibers comprise an antimicrobial material.
9. The bandage of claim 1 , wherein the nanofibers comprise TiO 2 .
10. The bandage of claim 1 , wherein the substrate comprises a woven fabric.
11. The bandage of claim 1 , wherein the substrate comprises a mesh.
12. The bandage of claim 2 , wherein the mesh comprises a polymer mesh.
13. The bandage of claim 1 , wherein a substantial portion of the nanowires are attached to the interior walls of the substrate.
14. The bandage of claim 1 , wherein the nanofibers are primarily attached to the interior wall surface area of the plurality of apertures.
15. The bandage of claim 1 , wherein the nanofibers attached to the interior wall surface area of the plurality of apertures have a total volume which is substantially smaller than the volume of said apertures.
16. The bandage of claim 1 , wherein the nanofibers attached to the substrate only slightly narrow the apertures of the substrate.
17. The bandage of claim 1 , further comprising a second substrate having a plurality of apertures disposed therethrough.