Chewable enteric coated aspirin tablets
View Patent ↗The invention relates to a tablet capable of being chewed or disintegrated in the oral cavity, which comprises an enteric coated aspirin active ingredient, and preferably a lightly compressed matrix comprising directly compressible carbohydrate(s) and at least one sweetener.
1. A tablet capable of being chewed or disintegrated in the oral cavity prior to swallowing comprising:
enteric coated aspirin particles, wherein the enteric-coated aspirin particles have a film coating formed from a dispersion of triethyl citrate and an anionic copolymer of methacrylic acid and methacrylates, wherein said enteric coated aspirin particles are not granulated during processing, and
wherein the aspirin particles comprise a matrix comprising (a) about 75% to about 90% by weight of dextrose monohydrate, and (b) about 0.05% to about 2.0% saccharin.
2. A tablet according to claim 1 wherein the aspirin particles have an average particle size from about 100 to about 500 microns.
3. A tablet according to claim 1 , wherein the aspirin particles are in the form of crystals.
4. A tablet according to claim 1 , wherein said tablet satisfies the USP test standards for enteric aspirin tablets.