Method for autologous transplantation
The present invention describes various support matrices to which cells can adhere and proliferate. Such support matrices are useful for implantation in a wound site to promote healing and regeneration of damaged tissue. The present invention further describes an article including a membrane having at least one layer having a porous surface and also including submucosal intestine tissue, and cells adhered to the layer. The present invention further describes that the cells adhered to the layer include chondrocyte cells.
1 . An article comprising a membrane having at least one layer having a porous surface and including submucosal intestine tissue, and cells adhered to said layer.
2 . An article according to claim 1 , wherein said cells are chondrocyte cells.
3 . An article according to claim 1 , wherein said membrane is cell-free.
4 . An article according to claim 1 , wherein said membrane is collagen.
5 . An article according to claim 1 , wherein said membrane is Type I and Type III collagen.
6 . An article according to claim 1 , wherein said membrane is resorbable.
7 . An article according to claim 1 , wherein said chondrocyte cells are autologous.
8 . An article according to claim 1 , further comprising biocompatible adhesive adjacent said membrane.
9 . An article according to claim 1 , wherein said membrane is adapted to be disposed over the articular cartilage defect.
10 . An article according to claim 1 , wherein said membrane is adapted to be disposed in the articular cartilage defect.
11 . An article according to claim 1 , wherein said membrane is disposed over the articular cartilage defect.
12 . An article according to claim 1 , wherein said membrane is disposed in the articular cartilage defect.