Diffusion-controllable coatings on medical device
View Patent ↗The present invention provides a method for forming on a medical device, preferably an ophthalmic lens, more preferably a contact lens, a diffusion-controllable coating capable of controlling the out-diffusion or release of guest materials from the medical device. The method of the invention comprises: (1) applying one layer of clay and optionally one or more layers of polyionic materials onto the medical device; or (2) applying alternatively a layer of a first polyionic material and a layer of a second polyionic material having charges opposite of the charges of the first polyionic material onto the medical device and releasing the coated medical device into a releasing medium having a composition capable of imparting a desired permeability to the diffusion-controllable coating on the medical device.
1. A method for forming a diffusion-controllable coating on a medical device, comprising:
applying at least one layer of clay onto the medical device to control the release of guest materials from the medical device, wherein the layer of clay consisting essentially of clay.
2. A method of claim 1 , further comprising applying at least one layer of a first polyionic material.
3. A method of claim 2 , wherein the clay is montmorillonite.
4. A method of claim 2 , further comprising applying one or more layers of a second polyionic material.
5. A method of claim 4 , wherein the medical device is an ophthalmic lens.
6. A method of claim 5 , wherein the ophthalmic lens is a contact lens.
7. A method for manufacturing ophthalmic lenses without an extraction process, comprising:
(1) producing ophthalmic lenses by molding in molds; and
(2) forming a coating on each of the ophthalmic lenses produced in step (1) to control the release of guest materials from the ophthalmic lenses by:
applying thereon one layer of clay, wherein the layer of clay consisting essentially of clay; and
optionally applying a layer of a first polyionic material onto the ophthalmic lenses.
8. A method of claim 7 , wherein said method comprises applying a layer of a second polyionic material.
9. A method of claim 8 , wherein the clay is montmorillonite.