Functionalized porous poly(aryl ether ketone) materials and their use
Functionalized porous poly(aryl ether ketone) articles are prepared by reacting ketone groups in the backbone of poly(aryl ether ketone) polymer with a primary amine reagent. Preferred functional primary amines are primary aliphatic amines or substituted hydrazines containing one or more target functional groups including polar groups, such as hydroxyl groups, ˜OH, amino groups, ˜NH 2 , ˜NHR, ˜NRR′, and ethylene oxide groups, ˜OCH 2 CH 2 —, negatively or positively charged ionic groups, such as ˜SO 3 − , ˜COO − , and ˜NH 4 + groups, hydrophobic groups such as siloxane or perfluorcarbone groups, and non-polar groups, such as linear or branched hydrocarbon groups. The functionalized porous poly(aryl ether ketone) article can be prepared by reacting primary amine with a pre-formed, shaped porous poly(aryl ether ketone) article or by functionalizing the surface of a non-porous precursor article that is subsequently converted into a porous article.
1. A functionalized porous poly(aryl ether ketone) article formed by reacting ketone groups in poly(aryl ether ketone) polymer with a primary amine reagent.
2. The porous article of claim 1 wherein said primary amine reagent comprises a primary aliphatic amine or a substituted hydrazine that contains one or more functional groups.
3. The porous article of claim 2 wherein said functional group comprises a polar group, a negatively or a positively charged ionic group, a hydrophobic group or a non-polar group.
4. The porous article of claim 1 wherein said primary amine reagent is reacted with said ketone groups in a pre-formed porous poly(aryl ether ketone) article or with said ketone groups in a non-porous precursor poly(aryl ether ketone) article that is subsequently converted into a porous article.
5. The porous article of claim 1 wherein said reaction with said primary amine reagent is carried out throughout the porous structure of said article or selectively at the exterior surface of said porous article only.
6. The porous article of claim 5 wherein said primary amine reagent comprises an oligomer or a polymer reacted with said exterior surface of said porous article.
7. The porous article of claim 6 wherein said primary amine reagent comprises an amino-functional silicone, an amino-functional perfluorohydrocarbon, an amino-functional ethylene oxide, or a polyethylene imine.
8. The porous article of claim 1 wherein said article comprises a fluid separation membrane, a membrane contactor, a membrane separator or chromatographic media.
9. The porous article of claim 3 wherein said polar group comprises a hydroxyl group, a primary, a secondary or a tertiary amino group, or an ethylene oxide group.
10. The porous article of claim 3 wherein said negatively or positively charged ionic group comprises a carboxylic group, a sulfonic acid group or a quaternary amino group.
11. The porous article of claim 3 wherein said hydrophobic group comprises a siloxane group or a perfluorohydrocarbon group.
12. The porous article of claim 3 wherein said non-polar group comprises a linear or branched hydrocarbon group.
13. The porous article of claim 1 wherein said porous poly(aryl ether ketone) article is semi-crystalline.
14. The porous article of claim 1 wherein said poly(aryl ether ketone) comprises poly(ether ether ketone).
15. The porous article of claim 2 wherein said primary aliphatic amine comprises hydroxylamine, monoethanolamine, monopropanolamine, monobutanolamine, ethylenediamine, propylenediamine, butylenediamine, poly(ethylene imine), 4-aminobutyric acid, 6-aminocaproic acid, 8-aminocaprylic acid or 3-amino-1-propanesulfonic acid.
16. The porous article of claim 2 wherein said functional group is utilized to bind molecules that contain one or more functional groups.
17. The porous article of claim 16 wherein said functional groups in said molecule are utilized to bind a protein.
18. The process of claim 16 wherein said functional groups in said molecule comprise epoxide groups, primary, secondary or tertiary amino groups, isocyanate groups, silane groups or triazine groups.
19. The porous article of claim 2 wherein said functional group is utilized to bind a functional perfluorohydrocarbon or functional siloxane.
20. The porous article of claim 19 wherein said article comprises a membrane contactor.