Granted Patent
B2
US 7,582,726 · App. 10/985,013 · Granted Sep 1, 2009
VEGF receptor antagonists
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Abstract
The present invention describes an approach to cancer therapy utilizing novel VEGF receptor antagonists. Specifically, the invention provides peptides and polynucleotides encoding VEGF receptor antagonists and methods of use thereof.
Claims (5)
1. A VEGF receptor antagonist consisting of KDR (Ig5-7).
2. A soluble VEGF receptor antagonist that consists essentially of SEQ ID NO:2.
3. A soluble VEGF receptor antagonist that consists essentially of SEQ ID NO:4.
4. The soluble VEGF receptor antagonist of claim 2 , consisting of SEQ ID NO:2.
5. The soluble VEGF receptor antagonist of claim 3 , consisting of SEQ ID NO:4.
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Apr 14, 2014
From: WAGNER, THOMAS E.
To: ORBIS HEALTH SOLUTIONS LLC
Reel/Frame 032665/0086 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Dec 31, 2009
From: GHC RESEARCH DEVELOPMENT CORPORATION AND GREENVILLE HOSPITAL SYSTEM
To: WAGNER, THOMAS E.
Reel/Frame 023720/0296 →