Implantable prosthetic valve
View Patent ↗A prosthetic valve for implantation within a fluid conducting lumen within a body includes an elongate generally cylindrical radially collapsible valve body scaffold defining a fluid passageway therethrough for retentive positioning within the lumen. A radially collapsible leaf valve member is supported by the scaffold includes a number of valve leafs deflectable between a closed position restricting fluid flow through the passageway and an open position permitting fluid flow through the passageway. The leaf valve member includes an interior leaf valve frame defining a valve leaf aperture which is sealed by a fluid impermeable non-thrombogenic lining to prevent fluid flow therethrough.
1. A valve, comprising:
a radially-elastic scaffold with valve leaflet frames having an open-frame construction; and
an elongate liner adjacent the radially-elastic scaffold and valve leaflet frames to provide a fluid passageway, where the elongate liner includes excess material to provide a concave shape to the elongate liner extending into the open-frame construction, and where the valve leaflet frames with the elongate liner move between a closed position to restrict fluid flow through the fluid passageway and an open position to allow fluid flow through the passageway.
2. The valve of claim 1 , further including a microfilter support mesh over the open-frame construction of the valve leaflet frames to support cultured tissue cells seeded on to the elongate liner.
3. The valve of claim 1 , wherein the valve leaflet frames of the radially-elastic scaffold are mechanically biased towards the open position.
4. The valve of claim 1 , wherein the valve leaflet frames of the radially-elastic scaffold are mechanically biased towards the closed position.
5. The valve of claim 1 , wherein the elongate liner is positioned over the radially-elastic scaffold and a second liner is positioned on the radially-elastic scaffold opposite the elongate liner.
6. The valve of claim 1 , wherein the radially-elastic scaffold attaches to an interior surface of a second radially collapsible prosthetic fluid conduit.
7. The valve of claim 6 , wherein the second radially collapsible prosthetic fluid conduit is a stent.
8. A valve, comprising:
a radially deformable unitary open-frame scaffold having a tubular body and valve leaflet frames; and
a liner at least partially encasing the radially deformable unitary open-frame scaffold to provide a fluid passageway, where the liner includes excess material to provide a concave shape to the liner extending into the open-frame scaffold, and where the valve leaflet frames with the liner move between a closed position to restrict fluid flow through the fluid passageway and an open position to allow fluid flow through the passageway.
9. The valve of claim 8 , further including a flexible hinge supporting each of the valve leaflet frames on the tubular body.
10. The valve of claim 8 , wherein the radially deformable unitary open-frame scaffold expands from a first diameter to a second radially-expanded diameter.
11. The valve of claim 10 , wherein the radially deformable unitary open-frame scaffold expands through the use of a delivery balloon.
12. The valve of claim 10 , wherein the radially deformable unitary open-frame scaffold is formed from a shape memory material that self-expands from the first diameter to the second radially-expanded diameter.
13. The valve of claim 8 , wherein the elongate liner is positioned over the radially deformable unitary open-frame scaffold and a second liner is positioned on the radially deformable unitary open-flame scaffold opposite the elongate liner.
14. A medical system, comprising:
a valve having:
a radially-elastic scaffold with valve leaflet frames having an open-frame construction; and
an elongate liner adjacent the radially-elastic scaffold and valve leaflet frames to provide a fluid passageway, where the elongate liner includes excess material to provide a concave shape to the elongate liner extending into the open-frame construction, and where the valve leaflet frames with the elongate liner move between a closed position to restrict fluid flow through the fluid passageway and an open position to allow fluid flow through the passageway; and
a second radially collapsible prosthetic fluid conduit, wherein the radially-elastic scaffold attaches to an interior surface of the second radially collapsible prosthetic fluid conduit.
15. The medical system of claim 14 , wherein the second radially collapsible prosthetic fluid conduit is a stent.
16. The medical system of claim 14 , wherein the valve leaflet frames of the radially-elastic scaffold are mechanically biased towards the open position.
17. The medical system of claim 14 , wherein the valve leaflet frames of the radially-elastic scaffold are mechanically biased towards the closed position.
18. The medical system of claim 14 , wherein the elongate liner is positioned over the radially-elastic scaffold and a second liner is positioned on the radially-elastic scaffold opposite the elongate liner.