IP Library Granted Patent US 7,462,179
Granted Patent B2
US 7,462,179 · App. 10/986,687 · Granted Dec 9, 2008

GERD treatment apparatus and method

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Quick Facts
Patent No.
US 7,462,179
App. No.
10/986,687
Granted
Dec 9, 2008
Kind
B2
Abstract

An apparatus includes an expandable member. The expandable member is sized to be positionable in a sphincter. An energy delivery device is positioned on a surface of the expandable member. The energy delivery device has a configuration that provides sufficient energy delivery to create lesions in the interior of the sphincter. When the expandable member is removed from the sphincter, the sphincter returns to its closed or contracted configuration.

Claims (19)

1. A method of treating a lower esophageal sphincter, comprising:

providing an expandable member sized to be positionable at or near a lower esophageal sphincter in a compacted condition and being sized and configured to expand to an expanded condition to non-permanently dilate the lower esophageal sphincter, and an energy delivery device coupled to the expandable member comprising at least one tissue-piercing needle electrode sized and configured for deployment between a retracted position and an extended position,

coupling a source of radio-frequency energy to the energy delivery device,

introducing the expandable member to a tissue region at or near the lower esophageal sphincter in the compacted condition and with the at least one tissue-piercing needle electrode in the retracted position,

expanding the expandable member to the expanded condition to dilate the lower esophageal sphincter,

deploying the at least one tissue-piercing needle electrode to the extended position to pierce sub-mucosal tissue at or near the lower esophageal sphincter,

delivering energy from the source of radio-frequency energy to the at least one needle-piercing electrode to cause necrosis of the sub-mucosal tissue due to resistance heating at or near the lower esophageal sphincter and produce at least one sub-mucosal lesion to thereby selectively tighten the lower esophageal sphincter,

returning the expandable member to the compacted condition and the at least one tissue-piercing electrode to the retracted position, and

removing the expandable member from the tissue region.

2. The method of claim 1

wherein the energy delivery device includes a plurality of tissue-piercing needle electrodes configured for deployment between a retracted position and an extended position,

wherein deploying deploys the plurality of tissue-piercing needle electrodes to the extended position to pierce sub-mucosal tissue at or near the lower esophageal sphincter, and

wherein delivering energy delivers radio-frequency energy to the plurality of tissue-piercing needle electrodes to produce a plurality of sub-mucosal lesions.

3. The method of claim 2

wherein the plurality of sub-mucosal lesions are produced at a fixed depth from the mucosal surface layer of no more than about 4 mms.

4. The method of claim 1

wherein the expandable member is a balloon.

5. The method of claim 1

wherein expanding the expandable member to the expanded condition dilates the lower esophageal sphincter between 5 and 40 mm.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 24, 2009
From: RESPIRATORY DIAGNOSTIC, INC.
To: MEDERI THERAPEUTICS, INC.
Reel/Frame 022597/0080 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 22, 2008
From: CURON MEDICAL, INC. BY JOHN T. KENDALL, TRUSTEE
To: RESPIRATORY DIAGNOSTIC, INC.
Reel/Frame 020986/0312 →