Plant-derived protein extract compositions and methods
Disclosed are skin care compositions comprising a plant-derived protein extract, such as a soy protein extract or a colloidal oatmeal preparation, supplemented by an enrichment composition, such as a non-alpha tocopherol, and methods of making and using such compositions.
1 . A skin care composition, comprising
a plant protein extract supplemented with at least 1% (w/w) of a non-alpha tocopherol or a non-alpha tocopherol enriched tocopherol composition.
2 . The skin care composition of claim 1 , wherein said non-alpha tocopherol is beta tocopherol.
3 . The skin care composition of claim 1 , wherein said non-alpha tocopherol is delta tocopherol.
4 . The skin care composition of claim 1 , wherein said non-alpha tocopherol is gamma tocopherol.
5 . The skin care composition of claim 1 , wherein said plant protein extract is a soy protein extract.
6 . The skin care composition of claim 5 , wherein said non-alpha tocopherol is beta tocopherol.
7 . The skin care composition of claim 5 , wherein said non-alpha tocopherol is delta tocopherol.
8 . The skin care composition of claim 5 , wherein said non-alpha tocopherol is gamma tocopherol.
9 . The skin care composition of claim 5 , wherein said soy protein extract retains protein function, as evidenced by at least about 80% of the trypsin inhibitory activity present in the starting material from which the soy protein extract is produced.
10 . The skin care composition of claim 5 , wherein said soy protein extract is essentially depleted of mammalian estrogen receptor binding activity.
11 . The skin care composition of claim 10 , wherein said soy protein extract contains less than about 10% of the mammalian estrogen receptor binding activity present in the soy material from which the extract is generated.
12 . The skin care composition of claim 10 , wherein said soy protein extract contains less than about 5% of the mammalian estrogen receptor binding activity present in the soy material from which the extract is generated.
13 . The skin care composition of claim 10 , wherein said soy protein extract contains less than about 1% of the mammalian estrogen receptor binding activity present in the soy material from which the extract is generated.
14 . The skin care composition of claim 5 , which further includes a retinoid.
15 . The composition of claim 14 , wherein said retinoid is retinoic acid.
16 . The skin care composition of claim 5 , formulated for topical administration to the skin of a mammalian subject.
17 . The skin care composition of claim 16 , wherein said composition is included in a topical cosmetic formulation.
18 . The skin care composition of claim 16 , wherein said composition is included in a topical pharmaceutical formulation.
19 . The skin care composition of claim 5 , wherein said composition is formulated for inclusion in a body waste containment article.
20 . The skin care composition of claim 5 , formulated for transdermal administration to a mammalian subject.
21 . The skin care composition of claim 5 , formulated for oral administration to a mammalian subject.
22 . The skin care composition of claim 21 , wherein said composition is formulated as a nutritional cosmetic formulation.
23 . The skin care composition of claim 1 , wherein said plant protein extract is a colloidal oatmeal preparation.
24 . The skin care composition of claim 23 , wherein said colloidal oatmeal preparation is essentially depleted of estrogen receptor binding activity.
25 . The skin care composition of claim 24 , wherein said colloidal oatmeal preparation contains less than about 5% of the mammalian estrogen receptor binding activity present in the soy material from which the extract is generated.
26 . The skin care composition of claim 24 , wherein said colloidal oatmeal preparation contains less than about 2% of the mammalian estrogen receptor binding activity present in the soy material from which the extract is generated.
27 . The skin care composition of claim 24 , wherein said colloidal oatmeal preparation contains less than about 1% of the mammalian estrogen receptor binding activity present in the soy material from which the extract is generated.
28 . The skin care composition of claim 23 , wherein said non-alpha tocopherol is delta-tocopherol.
29 . The skin care composition of claim 23 , wherein said non-alpha tocopherol is beta-tocopherol.
30 . The skin care composition of claim 23 , wherein said non-alpha tocopherol is gamma-tocopherol.
31 . The skin care composition of claim 23 , wherein said composition is formulated for topical delivery to the skin.
32 . The skin care composition of claim 31 , formulated for inclusion in a body waste containment article.
33 . The skin care composition of claim 23 , wherein said composition is formulated for oral delivery.
34 . A baby skin care composition, comprising a plant protein extract supplemented with at least 1% (w/w) of a non-alpha tocopherol or a non-alpha tocopherol enriched tocopherol composition.
35 . The baby skin care composition of claim 34 , wherein said plant protein extract is a soy protein extract.
36 . The baby skin care composition of claim 34 , wherein said plant protein extract is a colloidal oatmeal preparation.
37 . The baby skin care composition of claim 34 , wherein said non-alpha tocopherol is beta tocopherol.
38 . The baby skin care composition of claim 34 , wherein said non-alpha tocopherol is delta tocopherol.
39 . The baby skin care composition of claim 34 , wherein said non-alpha tocopherol is gamma tocopherol.
40 . The baby skin care composition of claim 35 , wherein said soy protein extract retains protein function, as evidenced by at least about 80% of the trypsin inhibitory activity present in the starting material from which the soy protein extract is produced.
41 . The baby skin care composition of claim 35 , wherein said soy protein extract is essentially depleted of mammalian estrogen receptor binding activity.
42 . The baby skin care composition of claim 35 , wherein said soy protein extract contains less than about 5% of the mammalian estrogen receptor binding activity present in the soy material from which the extract is generated.
43 . The baby skin care composition of claim 35 , wherein said soy protein extract contains less than about 2% of the mammalian estrogen receptor binding activity present in the soy material from which the extract is generated.
44 . The baby skin care composition of claim 35 , wherein said soy protein extract contains less than about 1% of the mammalian estrogen receptor binding activity present in the soy material from which the extract is generated.
45 . The baby skin care composition of claim 34 , formulated for topical administration to the skin of a mammalian baby.
46 . The baby skin care composition of claim 45 , wherein said composition is formulated for inclusion in a body waste containment article.
47 . The baby skin care composition of claim 34 , wherein said composition is included in a topical pharmaceutical formulation.
48 . The baby skin care composition of claim 34 , formulated for transdermal administration to a mammalian baby.
49 . The baby skin care composition of claim 34 , formulated for oral administration to a mammalian baby.
50 . A method of treating or ameliorating the symptoms of an inflammatory skin condition in a mammalian subject, comprising
administering to the subject a cosmetically or pharmaceutically effective amount of a composition according to claim 1 .
51 . The method of claim 50 , wherein the inflammatory skin condition is retinoid-induced skin irritation.
52 . The method of claim 50 , wherein the inflammatory skin condition is sunburn.
53 . The method of claim 50 , wherein the inflammatory skin condition is diaper rash.
54 . A skincare kit, comprising
a composition according to claim 1 , and
instructions for applying such composition to the skin of a mammalian subject.