IP Library › Granted Patent US 7,291,451
Granted Patent B2
US 7,291,451 · App. 10/993,142 · Granted Nov 6, 2007

Modulation of pericyte proliferation

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Quick Facts
Patent No.
US 7,291,451
App. No.
10/993,142
Granted
Nov 6, 2007
Kind
B2
Abstract

Methods and materials for modulating pericyte and epithelial cell proliferation relating to BPI protein products or inhibitors thereof are provided.

Claims (2)

1. A method of screening a BPI protein product for the ability to enhance proliferation of pericytes comprising the steps of: (a) detecting proliferation of pericytes in the presence and absence of a BPI protein product; and (b) identifying a BPI protein product as a candidate enhancer of pericyte proliferation when proliferation of the pericytes is increased in the presence of the BPI protein product.

2. The method of claim 1 wherein proliferation is determined by measuring the amount of MAP kinase phosphorylation.