Granted Patent
B2
US 7,408,008 · App. 11/006,145 · Granted Aug 5, 2008
Method of producing highly functionalized 1,3-diamino-propan-2-ols from solid support
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Abstract
The invention is directed to compounds and methods of synthesizing hydroxyethlamino amides and their use in treatment of aspartyl protease mediated diseases and conditions.
Claims (4)
1. A compound of formula (Ia):
wherein (support) is selected from the group consisting of amine based polystyrene resins.
2. The compound according to claim 1 wherein (support) is a Rink type resin.
3. The compound according to claim 1 wherein (support) is Rink-AM resin.
Assignments (4)
TERMINATION AND RELEASE OF SECURITY INTEREST
Recorded Aug 28, 2018
From: EAST WEST BANK
To: ULTRA CLEAN HOLDINGS, INC.
Reel/Frame 046962/0550 →
SECURITY INTEREST
Recorded Feb 4, 2015
From: ULTRA CLEAN HOLDINGS, INC.
To: EAST WEST BANK
Reel/Frame 034887/0730 →
SECURITY AGREEMENT
Recorded Jul 3, 2012
From: ULTRA CLEAN HOLDINGS, INC.
To: SILICON VALLEY BANK
Reel/Frame 028497/0156 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Sep 14, 2005
From: COATS, STEVE J.; HLASTA, DENNIS J.; SCHULZ, MARK J.
To: JANSSEN PHARMACEUTICA N.V.
Reel/Frame 016790/0556 →