Direct one-step synthesis of trifluoromethyl iodide
View Patent ↗A catalytic one-step process for the production of CF 3 I by reacting, in the presence of a source of oxygen, a source of iodine a reactant of the formula: CF 3 R where R is —COOH, —COX, —CHO, —COOR 2 and —SO 2 X, where R 2 is an alkyl group and X is selected from chlorine, bromine and iodine. The catalyst may be a metal salt such as salts of Cu, Hg, Pt, Pd, Co, Mn, Rh, Ni, V, Tl, Ba, Cs, Ca, K and Ge and mixtures thereof, preferably on a support, such as MgO, BaO and CaO, BaCO 3 , CsNO 3 , Ba (NO 3 ) 2 , activated carbon, basic alumina, and ZrO 2 .
1. A process for the production of CF 3 I, the process comprising reacting, in the presence of at least a stoichiometric amount of oxygen, a source of iodine selected from the group consisting of iodine, hydrogen iodide and iodine monochloride with a reactant selected from the group consisting of those of the formula:
CF 3 R
where R is selected from the group consisting —COX, —CHO, —COOR 2 and —SO 2 X, where R 2 is an alkyl group and X is selected from chlorine, bromine and iodine, in the presence of a catalyst.
2. A process according to claim 1 wherein the reaction is conducted as a vapor phase reaction.
3. A process according to claim 1 wherein the reaction is conducted as a liquid phase reaction.
4. A process according to claim 1 wherein the reaction is conducted at a temperature of from about 50° to about 600° C.
5. A process according to claim 1 wherein the metal salt catalyst is selected from salts of Cu, Hg, Pt, Pd, Co, Mn, Rh, Ni, V, Tl, Ba, Cs, Ca, K and Ge and mixtures thereof.
6. A process according to claim 5 wherein the metal salt is on a support material.
7. A process according to claim 6 wherein the support material is selected from the group consisting of a basic oxide, BaCO 3 , CsNO 3 , Ba(NO 3 ) 2 , activated carbon, basic alumina, and ZrO 2 .
8. The process of claim 7 wherein the catalyst is Cu(II)-Pt(II)/activated carbon.
9. The process according to claim 8 wherein the reaction is conducted in the presence of air as the source of oxygen.
10. A process according to claim 1 wherein the reaction is conducted in the presence of air as the source of oxygen, iodine is employed as the source of iodine, and the catalyst is Cu(II)-Pt(II)/activated carbon.