Analgesic and anti-inflammatory compositions containing Cox-2-inhibitors
View Patent ↗The present invention is directed to an analgesic composition which consists essentially of a cyclooxygenase-2 inhibitor and a compound selected from the group consisting of non-steroidal anti-inflammatory drugs, acetaminophen and mixtures thereof. The present invention further is directed to a method for inducing analgesia through the administration of such a composition to a patient.
1. A method of alleviating pain comprising administering to a mammal exhibiting pain a composition consisting essentially of (a) celecoxib and (b) racemic ketoprofen wherein the pain alleviation effect of the racemic ketoprofen is potentiated by the celecoxib.
2. The method of claim 1 wherein celecoxib is present in amounts ranging from about 25 to about 200 mg and racemic ketoprofen is present in amounts ranging from about 6.5 to about 25 mg.
3. The method of claim 1 wherein celecoxib is present in amounts ranging from about 100 to about 200 mg and racemic ketoprofen is present in amounts ranging from about 12.5 to about 25 mg.
4. The method of claim 1 wherein celecoxib is present in an amount of about 200 mg and racemic ketoprofen is present in an amount of about 25 mg.