Use of natural plant extracts in cosmetic compositions
View Patent ↗The present invention describes compositions and methods for treating, preventing and improving the appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating loss of subcutaneous fat in the skin, wherein the compositions include natural plant constituents that stimulate lipid synthesis. The plant extracts are preferably derived from Rhinacanthus nasutus, Humulus scandens, Sesbania grandiflora, Amorphophallus campanulatu, Pouzolzia pentandra , and Piper betel , and any combinations thereof. The compositions are preferably applied to the skin, or are delivered by directed means, to a site in need thereof.
1. A method for treating loss of subcutaneous fat, comprising topically administering to a subject in need thereof a composition comprising a cosmetically, dermatologically, or pharmaceutically effective amount of at least one plant extract sufficient to stimulate lipid production, adiponectin production, adipocyte differentiation, PPAR-gamma induction, and/or any combinations thereof in an amount effective to ameliorate and/or reduce loss of subcutaneous fat, wherein said at least one plant extract is obtained from Humulus scandens, Amorphophallus campanulatu , or Pouzolzia pentandra , either alone or in combination with each other; and a cosmetically, dermatologically, or pharmaceutically acceptable vehicle.
2. The method according to claim 1 , wherein said composition is applied for a period of time effective to ameliorate, reduce, and/or eliminate loss of subcutaneous fat.
3. The method according to claim 1 , wherein the at least one plant extract comprises Rhinacanthus nasutus, Humulus scandens, Sesbania grandiflora, Amorphophallus campanulatu, Pouzolzia pentandra , and Piper betel.
4. The method according to claim 1 , wherein the composition is applied at least once daily for at least one week.
5. The method according to claim 4 , wherein said at least one plant extract is present in an amount about 0.001 wt % to about 20 wt % based on the total weight of the composition.
6. The method according to claim 4 , wherein said at least one plant extract is present in an amount of from about 0.005 wt % to about 5 wt % of the total weight of the composition.
7. The method according to claim 1 , wherein the composition comprises a cosmetically or dermatologically acceptable vehicle, carrier or diluent.
8. The method according to claim 1 , wherein the composition is applied to the face and the plant extract stimulates lipid production in the subcutaneous layer of the skin, thereby replacing fat loss due to chronological or hormonal aging.
9. The method according to claim 1 , wherein the at least one plant extract further comprises Rhinacanthus nasutus, Sesbania grandiflora , and/ or Piper betel.