Production of water for injection using reverse osmosis
View Patent ↗A method and system for providing Water for Injection using reverse osmosis. Water for Injection can be produced by reverse osmosis and the reverse osmosis membrane can be kept in a constantly self-sanitizing condition. One way of obtaining a constantly self-sanitizing condition is to maintain the reverse osmosis membrane at an elevated temperature during production of Water for Injection.
1. A system for producing Water for Injection comprising:
a reverse osmosis unit comprising a water inlet, a water outlet, and a reverse osmosis membrane;
a temperature sensor positioned in the reverse osmosis unit;
a water heat exchanger positioned upstream of and fluidly connected to the reverse osmosis membrane;
a water pre-heater positioned upstream of and fluidly connected to the water heat exchanger and fluidly connected to a concentrate outlet of the reverse osmosis unit;
a controller responsive to a signal from the temperature sensor to provide a control signal to the water heat exchanger to maintain a water temperature at greater than or equal to 60 C. during water purification; and
a storage vessel downstream of and fluidly connected to the reverse osmosis unit wherein the storage vessel maintains Water for Injection at an elevated temperature.
2. The system of claim 1 , wherein the reverse osmosis membrane is made of a material capable of withstanding a temperature greater than or equal to 60° C.
3. The system of claim 2 , further comprising means for continuously providing a trans-membrane stream at a pressure of greater than about 40 psig.
4. The system of claim 1 , wherein the reverse osmosis membrane is made of a material capable of withstanding a temperature greater than or equal to 80° C.
5. The system of claim 1 , wherein the storage vessel is constructed and arranged to maintain a temperature greater than or equal to 65° C.
6. The system of claim 1 , further comprising a recycle loop providing fluid communication between a downstream side of the reverse osmosis membrane and the water heat exchanger.
7. The system of claim 1 , further comprising a pre-treatment device upstream of and fluidly connected to the water heat exchanger.