IP Library Granted Patent US 7,282,046
Granted Patent B2
US 7,282,046 · App. 11/041,715 · Granted Oct 16, 2007

Glaucoma treatment method

Assignee: Peter M. Adams, Doug P. Adams, and John Sullivan, Collectively as the Stockholder Representative Committee
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Quick Facts
Patent No.
US 7,282,046
App. No.
11/041,715
Granted
Oct 16, 2007
Kind
B2
Abstract

Embodiments of the present invention provide a method and system of treating intraocular pressure. Laser light is directed to the ciliary region of the target eye. The light stimulates the ciliary region and ablates debris lodged therein. An immune response may be triggered by the stimulation of the ciliary body. Intraocular pressure is reduced by the increase in aqueous flow from the anterior chamber in the eye permitted by the resultant removal of debris blocking the uveo-scleral outflow pathway.

Claims (20)

1. A method for the therapeutic reduction of intraocular pressure in a mammalian eye, said method comprising:

Directing a laser light from a laser delivery device external to said eye to a ciliary region of said eye; said laser light being selected to ablate debris within said ciliary region without destruction of surrounding tissues,

Stimulating said ciliary region;

Ablating debris lodged in said ciliary region without perforation of tissues of said eye within said ciliary region.

2. The method according to claim 1 wherein said laser light has a depth penetration not less than 50 μm.

3. The method according to claim 1 wherein said laser light has a depth penetration not less than 70 μm.

4. The method according to claim 1 wherein said laser light has a depth penetration not less than 200 μm.

5. The method according to claim 1 , further comprising targeting a ciliary trabeculum of said ciliary region with said laser light.

6. The method according to claim 5 further comprising evoking an immune response.

7. The method according to claim 6 wherein said immune response comprises the activation of cytokines and macrophages.

8. The method according to claim 5 further comprising goniscopically applying said laser light to said ciliary trabeculum.

9. The method according to claim 1 further comprising targeting a ciliary body disposed within said ciliary region.

10. The method according to claim 9 further comprising evoking an immune response.

11. The method according to claim 10 wherein said immune response comprises the activation of cytokines and macrophages.

12. The method according to claim 9 further comprising compressing a sclera of said eye with said laser delivery device.

13. The method according to claim 9 further comprising transmitting said laser light through a sclera of said eye without a substantial effect on said sclera.

14. The method according to claim 13 further comprising treating a plurality of points on said sclera.

15. The method according to claim 1 wherein said laser light has a wavelength greater than 600 nm.

16. The method according to claim 1 wherein said laser light has a wavelength in the range of 700 nm to 1000 nm.

17. The method according to claim 1 wherein said laser light is generated by a titanium sapphire laser.

Assignments (6)
RELEASE OF SECURITY INTEREST Recorded Oct 15, 2010
From: TEARLAB CORPORATION (FORMERLY KNOWN AS OCCULOGIX, INC.)
To: SOLX, INC.
Reel/Frame 025137/0719 →
RELEASE OF SECURITY INTEREST Recorded Oct 15, 2010
From: PETER M. ADAMS, DOUG P. ADAMS, AND JOHN SULLIVAN, COLLECTIVELY AS THE STOCKHOLDER REPRESENTATIVE COMMITTEE, ON BEHALF OF THE PARTICIPATING RIGHTS HOLDERS OF SOLX, INC.
To: SOLX, INC.
Reel/Frame 025137/0725 →
CORRECTING TYPOGRAPHICAL ERROR OF A PATENT NUMBER PREVIOUSLY RECORDED ON REEL/FRAME 020571/0577 Recorded Mar 5, 2008
From: SOLX,INC.
To: OCCULOGIX, INC.
Reel/Frame 020599/0776 →
SECURITY AGREEMENT Recorded Jan 25, 2008
From: SOLX, INC.
To: DOUG P. ADAMS, JOHN SULLIVAN AND PETER M. ADAMS, COLLECTIVELY AS THE STOCKHOLDER REPRESENTATIVE COMMITTEE ON BEHALF OF THE PARTICIPATING RIGHTS HOLDERS OF SOLX, INC.
Reel/Frame 020403/0845 →
SECURITY AGREEMENT Recorded Jan 31, 2007
From: SOLX, INC.
To: PETER M. ADAMS, DOUG P. ADAMS, AND JOHN SULLIVAN, COLLECTIVELY AS THE STOCKHOLDER REPRESENTATIVE COMMITTEE, ON BEHALF OF THE PARTICIPATING RIGHTS HOLDERS OF SOLX, INC.
Reel/Frame 018826/0382 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 22, 2005
From: SIMON, GABRIEL
To: SOLX, INC.
Reel/Frame 015932/0526 →
Continuity (2)
Provisional Application 6053840700 · Jan 22, 2004
Related Publication 20050165385A1 · Jul 28, 2005