Stabilized feverfew formulations
The present invention is directed to compositions, methods of delivery and packaged nutraceuticals of a stabilized Feverfew Extract. More specifically, the stabilized Feverfew extract contains at least about 4% parthenolide. In a particular embodiment, the stabilized Feverfew extract is provided in a soft gelatin capsule, at a concentration effective to provide relief of the identified affliction, such as a migraine headache.
1 . A dietary supplement comprising, an extract from a Feverfew plant and magnesium wherein the Feverfew extract contains about 4.0% stabilized parthenolide and the magnesium is provided as magnesium oxide.
2 . A dietary supplement comprising, an extract from a Feverfew plant and magnesium wherein the Feverfew extract contains about 4.0% parthenolide stabilized with a stabilizing agent and the magnesium is provided as magnesium, wherein the stabilizing agent is a salt of an organic acid having two or more carboxylic acid moieties.
3 . The dietary supplement of claim 2 wherein the organic acid salt is tricalcium citrate.
4 . A soft gelatin capsule comprising an extract from a Feverfew plant wherein the Feverfew extract contains about 4.0% stabilized parthenolide.
5 . The soft gelatin capsule of claim 4 , further comprising a magnesium compound.
6 . The soft gelatin capsule of claim 5 , wherein the magnesium compound is magnesium oxide.
7 . The soft gelatin capsule of claims 5 , further comprising riboflavin.
8 . The soft gelatin capsule of claim 5 , further comprising vitamin B2.
9 . The soft gelatin capsule of claim 5 , further comprising Feverfew powder.
10 . The soft gelatin capsule of claim 5 , wherein the stabilized parthenolide is stabilized with a stabilizing agent comprising a salt of an organic acid having two or more carboxylic acid moieties.
11 . The soft gelatin capsule of claim 10 , wherein the stabilizing agent is tricalcium citrate.
12 . A method to treat or prevent inflammation, asthma, hayfever or migraine headaches, comprising administering an effective amount of a dietary supplement comprising, an extract from a Feverfew plant and magnesium wherein the Feverfew extract contains about 4.0% stabilized parthenolide and the magnesium is provided as magnesium oxide, such that the inflammation, asthma, hayfever or migraine headache is treated or prevented.
13 . A method to treat or prevent inflammation, asthma, hayfever or migraine headaches, comprising administering an effective amount of a dietary supplement comprising, an extract from a Feverfew plant and magnesium wherein the Feverfew extract contains about 4.0% parthenolide stabilized with a stabilizing agent and the magnesium is provided as magnesium oxide, wherein the stabilizing agent is a salt of an organic acid having two or more carboxylic acid moieties, such that the inflammation, asthma, hayfever or migraine headache is treated or prevented
14 . A method to treat or prevent inflammation, asthma, hayfever or migraine headaches, comprising administering an effective amount of a soft gelatin capsule comprising an extract from a Feverfew plant wherein the Feverfew extract contains about 4.0% stabilized parthenolide.
15 . The method of claim 14 , wherein the stabilized parthenolide is stabilized with a stabilizing agent comprising a salt of an organic acid having two or more carboxylic acid moieties.
16 . The method of claim 15 , wherein the stabilizing agent is tricalcium citrate.
17 . A packaged nutraceutical for treating or preventing inflammation, asthma, hayfever or migraine headaches comprising:
an effective amount of a nutraceutical supplement comprising, an extract from a Feverfew plant and magnesium wherein the Feverfew extract contains about 4.0% stabilized parthenolide and the magnesium is provided as magnesium oxide; and
instructions for administration of the dietary supplement to treat or prevent inflammation, asthma, hayfever or migraine headaches.
18 . A packaged nutraceutical for treating or preventing inflammation, asthma, hayfever or migraine headaches comprising:
an effective amount of a nutraceutical supplement comprising, an extract from a Feverfew plant and magnesium wherein the Feverfew extract contains about 4.0% parthenolide stabilized with a stabilizing agent and the magnesium is provided as magnesium oxide, wherein the stabilizing agent is a salt of an organic acid having two or more carboxylic acid moieties; and
instructions for administration of the dietary supplement to treat or prevent inflammation, asthma, hayfever or migraine headaches.
19 . A packaged nutraceutical for treating or preventing inflammation, asthma, hay fever or migraine headaches comprising:
an effective amount of a nutraceutical supplement comprising a soft gelatin capsule comprising an extract from a Feverfew plant wherein the Feverfew extract contains about 4.0% stabilized parthenolide; and
instructions for administration of the dietary supplement to treat or prevent inflammation, asthma, hay fever or migraine headaches.
20 . The packaged nutraceutical of claim 19 , wherein the stabilized parthenolide is stabilized with a stabilizing agent comprising a salt of an organic acid having two or more carboxylic acid moieties.