Granted Patent
B2
US 7,384,648 · App. 11/066,773 · Granted Jun 10, 2008
Implant device with a retinoid for improved biocompatibility
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Abstract
An implant device is provided which incorporates a retinoid for improving the biocompatibility of the device in tissue. The device may be bioerodible for the purpose of systemically or locally releasing a therapeutic agent in tissue or it may be a permanent implant which includes a surface treated with a retinoid for increasing the biocompatibility thereof.
Claims (1)
1. A tissue biocompatibility improving retinoid disposed in a retinal plug, said retinal plug having a hole through a proximal end thereof for enabling suturing of said retinal plug to a sclera with a distal end of said retinal plug inserted into a vitreous cavity, said retinoid comprising P-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyll-2-naphthyl)propenyl]-benzoic acid.