IP Library Granted Patent US 7,090,644
Granted Patent B2
US 7,090,644 · App. 11/069,585 · Granted Aug 15, 2006

Device for determining a characteristic point in the cardiac cycle

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Quick Facts
Patent No.
US 7,090,644
App. No.
11/069,585
Granted
Aug 15, 2006
Kind
B2
Abstract

The present invention relates to a device for determining a characteristic point in the cardiac cycle that comprises means for calculating the curve of the blood flow rate D(t) in the aorta from the curve of the arterial blood pressure signal P(t) and determining from the curve of the blood flow rate D(t) in each cardiac cycle the time at which an incisura point lies. The device can be used for activating an intra-aortal balloon pump (IABP).

Claims (10)

1. A method for activating an intra-aortal balloon pump (IABP) comprising:

(a) calculating the curve of the blood flow rate D(t) in the aorta from the curve of the arterial blood pressure signal P(t) and determining from the curve of the blood flow rate D(t) in each cardiac cycle the time at which an incisura point lies, wherein the incisura point is determined from a first local minimum in the curve of the blood flow rate D(t) after the beginning of an ejection phase;

(b) delivering a first signal when the incisura point is reached, wherein said first signal activates an intra-aortal balloon pump (IABP) to inflate; and

(c) delivering a second signal at the beginning of the ejection phase, wherein said second signal activates an intra-aortal balloon pump (IABP) to deflate.

2. The method according to claim 1 , wherein the blood flow rate D(t) lies below a threshold value Dd.

3. The method according to claim 2 , wherein Dd is equal to 10% of the blood flow rate when the blood flow rate from the left ventricle has reached its maximum value.

4. The method according to claim 2 , wherein Dd=0.

5. The method according to claim 1 , wherein the incisura point is determined when D(t)=0 after the beginning of an ejection phase.

6. The method according to claim 1 , which further comprises filtering out a high-frequency noise on the arterial blood pressure signal P(t).

7. The method according to claim 1 , wherein calculation of the curve of the blood flow rate D(t) in the aorta from the curve of the arterial blood pressure signal P(t) is based on the Windkessel model.

Assignments (5)
CONVERSION AND CHANGE OF NAME Recorded Sep 10, 2020
From: ARROW INTERNATIONAL, INC.
To: ARROW INTERNATIONAL LLC
Reel/Frame 053754/0731 →
SECURITY INTEREST Recorded Oct 3, 2019
From: ARROW INTERNATIONAL, INC.
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 050619/0681 →
MERGER Recorded Jun 3, 2019
From: ARROW INTERNATIONAL INVESTMENT CORP.
To: ARROW INTERNATIONAL, INC.
Reel/Frame 049348/0690 →
SECURITY INTEREST Recorded Feb 21, 2017
From: ARROW INTERNATIONAL INVESTMENT CORP.
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 041759/0707 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 9, 2017
From: HOEKSEL, SEBASTIAAN ADRIANUS ALPHONSUS PETRUS; SCHREUDER, JOHANNES JACOBUS; JANSEN, JOSEF REINIER CORNELUS
To: ARROW INTERNATIONAL INVESTMENT CORPORATION
Reel/Frame 041219/0622 →