IP Library Granted Patent US 7,455,862
Granted Patent B2
US 7,455,862 · App. 11/088,022 · Granted Nov 25, 2008

Herbal compositions useful in cancer treatment

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Quick Facts
Patent No.
US 7,455,862
App. No.
11/088,022
Granted
Nov 25, 2008
Kind
B2
Abstract

A herbal composition containing Curcumae kwangsiensis (Ezhu), Herba Dendrobii nobile Lindl. (Shihu), Rhizoma Pinelliae preparatum (Fabanxia), Rhizoma Typhonii (Baifuzi) and other optional herbs. The composition can be processed into a form for administering to human patients with a cancerous disease for improving their health.

Claims (78)

1. An anti-heparanase composition, comprising:

an effective amount of Curcumae kwangsiensis (Ezhu);

an effective amount of Herba Dendrobii nobile Lindl . (Shihu);

an effective amount of Rhizoma Pinelliae preparatum (Fabanxia); and

an effective amount of Rhizoma Typhonii (Baifuzi);

wherein the ratio by weight between Curcumae kwangsiensis (Ezhu) and Herba Dendrobii nobile Lindl . (Shihu) is 0.1-10;

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Rhizoma Pinelliae preparatum (Fabanxia) is 0.25-10; and

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Rhizoma Typhonii (Baifuzi) is 0.25-10.

2. The composition of claim 1 , further comprising:

an effective amount of Radix Sophora tonkinensis (Shandougen);

an effective amount of Radix Arnebia euchroma (Zicaogen);

an effective amount of Frutus lycium barbarum (Gouqizi);

an effective amount of Radix Astagalus membranaceus (Huangqi); and

an effective amount of Oldenlandia diffusa (Baihuasheshecao).

3. The composition of claim 2 , further comprising:

an effective amount of Rhizoma polygonati (Huangjing); and

an effective amount of Radix Glycyrrhizae (Gancao).

4. An anti-heparanase composition, comprising:

an effective amount of Curcumae kwangsiensis (Ezhu) extract;

an effective amount of Herba Dendrobii nobile Lindl. (Shihu) extract;

an effective amount of Rhizoma Pinelliae preparatum (Fabanxia) extract; and

an effective amount of Rhizoma Typhonii (Baifuzi) extract; said extract being a total extract, polysaccharide-enriched extract, or non-polysaccharide-enriched extract, and

wherein prior to extracting the ratio by weight between Curcumae kwangsiensis (Ezhu) and Herba Dendrobii nobile Lindl. (Shihu) is 0.1-10;

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Rhizoma Pinelliae preparatum (Fabanxia) is 0.25-10; and

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Rhizoma Typhonii (Baifuzi) is 0.25-10.

5. The composition of claim 4 , further comprising:

an effective amount of Radix Sophora tonkinensis (Shandougen) extract;

an effective amount of Radix Arnebia euchroma (Zicaogen) extract;

an effective amount of Frutus lycium barbarum (Gouqizi) extract;

an effective amount of Radix Astagalus membranaceus (Huangqi) extract; and

an effective amount of Oldenlandia diffusa (Baihuasheshecao) extract.

6. The composition of claim 5 , further comprising:

an effective amount of Rhizoma polygonati (Huangjing) extract; and

an effective amount of Radix Glycyrrhizae (Gancao) extract.

7. The composition of claim 2 , wherein:

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Radix Sophora tonkinensis (Shandougen) is 0.25-10;

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Radix Arnebia euchroma (Zicaogen) is 0.16-10;

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Frutus lycium barbarum (Gouqizi) is 0.16-5;

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Radix Astagalus membranaceus (Huangqi) is 0.16-5; and

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Oldenlandia diffusa (Baihuasheshecao) is 0.125-2.5.

8. The composition of claim 3 , wherein:

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Rhizoma polygonati (Huangjing) is 0.1-2.5; and

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Radix Glycyrrhizae (Gancao) is 0.25-10.

9. The composition of claim 1 , wherein:

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Herba Dendrobii nobile Lindl . (Shihu) is 0.5-5;

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Rhizoma Pinelliae preparatum (Fabanxia) is 1-5; and

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Rhizoma Typhonii (Baiftizi) is 1-5.

10. The composition of claim 7 , wherein:

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Radix Sophora tonkinensis (Shandougen) is 0.5-5;

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Radix Arnebia euchroma (Zicaogen) is 0.3-5;

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Frutus lycium barbarum (Gouqizi) is 0.3-2.5;

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Radix Astagalus membranaceus (Huangqi) is 0.3-2.5; and

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Oldenlandia diffusa (Baihuasheshecao) is 0.25-1.

11. The composition of claim 8 , wherein:

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Rhizoma polygonati (Huangjing) is 0.2-1; and

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Radix Glycyrrhizae (Gancao) is 0.5-5.

12. The composition of claim 5 , wherein prior to extracting:

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Radix Sophora tonkinensis (Shandougen) is 0.25-10;

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Radix Arnebia euchroma (Zicaogen) is 0.16-10;

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Frutus lycium barbarum (Gouqizi) is 0.16-5;

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Radix Astagalus membranaceus (Huangqi) is 0.16-5; and

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Oldenlandia diffusa (Baihuasheshecao) is 0.125-2.5.

13. The composition of claim 6 , wherein prior to extracting:

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Rhizoma polygonati (Huangjing) is 0.1-2.5; and

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Radix Glycyrrhizae (Gancao) is 0.25-10.

14. The composition of claim 4 , wherein prior to extracting:

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Herba Dendrobii nobile Lindl . (Shihu) is 0.5-5;

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Rhizoma Pinelliae preparatum (Fabanxia) is 1-5; and

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Rhizoma Typhonii (Baifuzi) is 1-5; said extract being a total extract, polysaccharide-enriched extract, or non-polysaccharide-enriched extract.

15. The composition of claim 12 , wherein prior to extracting:

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Radix Sophora tonkinensis (Shandougen) is 0.5-5;

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Radix Arnebia euchroma (Zicaogen) is 0.3-5;

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Frutus lycium barbarum (Gouqizi) is 0.3-2.5;

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Radix Astagalus membranaceus (Huangqi) is 0.3-2.5; and

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Oldenlandia diffusa (Baihuasheshecao) is 0.25-1; said extract being a total extract, polysaccharide-enriched extract, or non-polysaccharide-enriched extract.

16. The composition of claim 13 , wherein prior to extracting:

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Rhizoma polygonati (Huangjing) is 0.2-1; and

the ratio by weight between Curcumae kwangsiensis (Ezhu) and Radix Glycyrrhizae (Gancao) is 0.5-5; said extract being a total extract, polysaccharide-enriched extract, or non-polysaccharide-enriched extract.

Assignments (2)
SECURITY AGREEMENT Recorded Jun 2, 2006
From: BODYMEDIA, INC.
To: OXFORD FINANCE CORPORATION
Reel/Frame 017718/0063 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 24, 2005
From: TSIM, WAH KEUNG KARL; LI, XIAO YI
To: LEE'S PHARMACEUTICAL (HONG KONG) LIMITED
Reel/Frame 017119/0577 →