Process for preparing 3-hydroxythiolane
View Patent ↗A process for preparing 3-hydroxythiolane which is characterized in reacting a compound of the following formula, wherein X is halogen atom, and R 2 is substituted or unsubstituted alkyl group, substituted or unsubstituted aralkyl group, or substituted or unsubstituted aryl group, with a metal sulfide.
1. A process for preparing 3-hydroxythiolane of the formula,
which is characterized in reacting a compound of the following formula,
wherein X is halogen atom, and R 2 is substituted or unsubstituted alkyl group, substituted or unsubstituted aralkyl group, or substituted or unsubstituted aryl group, with a metal sulfide.
2. The process for preparing 3-hydroxythiolane (2) according to claim 1 , wherein R 2 in the compound of the formula (1) is substituted or unsubstituted aryl group.
3. The process for preparing 3-hydroxythiolane (2) according to claim 1 , wherein the metal sulfide is an alkali metal sulfide or an alkaline earth metal sulfide.
4. The process for preparing 3-hydroxythiolane (2) according to claim 1 , wherein the metal sulfide is sodium sulfide.
5. The process for preparing 3-hydroxythiolane (2) according to claim 1 , wherein the compound (1) and the compound (2) are optically active.
6. The process for preparing 3-hydroxythiolane (2) according to claim 2 , wherein the compound (1) and the compound (2) are optically active.
7. The process for preparing 3-hydroxythiolane (2) according to claim 3 , wherein the compound (1) and the compound (2) are optically active.