Herbal composition PHY906 and its use in chemotherapy
View Patent ↗This invention provides herbal compositions useful for increasing the therapeutic index of drugs, including those used in the treatment of disease, especially viral infections and neoplasms of cancer. This invention provides methods useful for improving the quality of life of an individual undergoing chemotherapy. Furthermore, this invention improves the treatment of disease by increasing the therapeutic index of chemotherapy drugs by administering the herbal composition PHY906 to a person undergoing such chemotherapy.
1. A composition comprising:
i) a pharmaceutically acceptable carrier;
ii) an herbal preparation consisting essentially of Scutellaria, Glycyrrhiza, Ziziphus and Paeonia ; and
iii) a chemotherapeutic formulation comprising one or more chemotherapeutic compounds selected from the group consisting of doxorubicin, thalidomide, capecitabine, gemcitabine, and oxaliplatin.
2. A composition of claim 1 , wherein the chemotherapeutic formulation further comprises 5-fluorouracil (5FU) and leucovorin (LV).
3. The composition of claim 1 , wherein the herbal preparation consists of Scutellaria baicalensis, Glycyrrhiza uralensis, Ziziphus jujuba, and Paeonia lactiflora.
4. A method of relieving side effects of a chemotherapeutic compound in a mammal comprising administering a composition comprising: i) a pharmaceutically acceptable carrier; ii) an herbal preparation consisting essentially of Scutellaria baicalensis, Glycyrrhiza uralensis, Ziziphus jujuba and Paeonia lactiflora ; and iii) a chemotherapeutic formulation comprising the chemotherapeutic compound selected from the group consisting of doxorubicin, thalidomide, capecitabine, gemcitabine, and oxaliplatin.