Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them

1. A compound of the formula

wherein

A is

X is —CO— or —NH—CO—;

and Y is —NH—Z 2 —Q— or piperazine, Q is selected from the group consisting of a single bond, O—Z 3 , R 3 —N—Z 3 and S—Z 3 , and Z 2 and Z 3 are independently a bond or alkylene of 1 to 6 carbon atoms and R 3 is hydrogen or alkyl of 1 to 6 carbon atoms;

B is alkyl of 1 to 6 carbon atoms or carbocyclic or heterocyclic aryl with 5 to 6 members containing 1 to 4 heteroatoms selected from the group consisting of O, S and N, the aryl being optionally substituted by at least one member selected from the group consisting of alkyl, alkenyl and alkoxy of up to 6 carbon atoms;

R 6 is hydrogen or OH;

and salts thereof.

2. A compound of claim 1 wherein

A is

X is —CO—;

and Y is —NH-Z 2 -Q- or piperazine, Q is selected from the group consisting of a single bond, O-Z 3 , R 3 —N-Z 3 and S-Z 3 , and Z 2 and Z 3 are independently a bond or alkylene of 1 to 6 carbon atoms and R 3 is hydrogen or alkyl of 1 to 6 carbon atoms;

B is alkyl of 1 to 6 carbon atoms or carbocyclic or heterocyclic aryl with 5 to 6 members containing 1 to 4 heteroatoms selected from the group consisting of O, S and N, the aryl being optionally substituted by at least one member selected from the group consisting of alkyl, alkenyl and alkoxy of up to 6 carbon atoms;

R 6 is hydrogen or OH;

and salts thereof

3. A compound of claim 1 wherein

A is

X is —CO—;

and Y is piperazine;

B is a heterocyclic aryl of 5 to 6 members containing from 1 to 4 heteroatoms selected from the group consisting of O, S and N, the aryl being optionally substituted by at least one member selected from the group consisting of alkyl, alkenyl and alkoxy of up to 6 carbon atoms;

R 6 is hydrogen,

and salts thereof

4. A compound of claim 1 wherein B is selected from the group consisting of thiophene, furan, pyrrole and thiazole.