Disalt inhibitors of IL-12 production
View Patent ↗This invention relates to disalt nitrogen-heteroaryl inhibitors of IL-12 production, and related methods and pharmaceutical compositions.
1. A disalt represented by the formula:
wherein each M − is a conjugate base of a Bronsted acid.
2. The disalt of claim 1 , wherein M − is the conjugate base of a Bronsted acid selected from the group consisting of hydrochloric acid, nitric acid, sulfuric acid, hydrobromic acid, hydroiodic acid, perchloric acid, phosphoric acid, alkylsulfonic acids, arylsulfonic acids, halogenated alkylsulfonic acids, halogenated acetic acids, picric acid, oxalic acid, citric acid, formic acid, ascorbic acid and benzoic acid.
3. The disalt of claim 2 , wherein M − is methanesulfonate.
4. The disalt of claim 2 , wherein M − is bromide.
5. The disalt of claim 2 , wherein M − is chloride.
6. A pharmaceutical composition comprising a pharmaceutically acceptable carrier and a disalt according to claim 1 .