IP Library Granted Patent US 8,114,906
Granted Patent B2
US 8,114,906 · App. 11/106,482 · Granted Feb 14, 2012

Essential fatty acids in the treatment and/or inhibition of depression in patients with coronary heart or artery disease

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Quick Facts
Patent No.
US 8,114,906
App. No.
11/106,482
Granted
Feb 14, 2012
Kind
B2
Abstract

A method of treating or inhibiting depression in a patient with cardiovascular disease, especially a patient suffering from coronary artery or vascular disease, the method including administering, preferably orally, to the patient a therapeutically effective amount of an essential fatty acid composition comprising preferably more than 25% by weight of eicosapentanoic acid ethyl ester (EPA), of docosahexaenoic acid ethyl ester (DHA), or of a mixture of eicosapentanoic acid ethyl ester (EPA) and docosahexaenoic acid ethyl ester (DHA), especially a mixture of EPA and DHA in an EPA/DHA ratio in the range from about 0.9 to about 1.5 at a dosage of from about 0.7 g to about 6 g per day.

Claims (4)

1. A method for treating or inhibiting depression in a patient with coronary heart disease or coronary artery disease, said method consisting of orally administering to said patient a therapeutically effective dosage of from 0.7 g to 6 g per day of an essential fatty acid composition comprising a mixture of eicosapentanoic acid ethyl ester (EPA) and docosahexaenoic acid ethyl ester (DHA) in an EPA/DHA ratio in the range from 0.9 to 1.5.

2. A method according to claim 1 , wherein said composition contains more than 25% by weight of the mixture of EPA and DHA.

3. A method according to claim 1 , wherein said composition contains from 30 to 100% by weight of the mixture of EPA and DHA.

4. A method according to claim 3 , wherein said composition contains 85% by weight of the mixture of EPA and DHA.

Assignments (5)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 18, 2013
From: ABBOTT PRODUCTS GMBH
To: ABBOTT LABORATORIES GMBH
Reel/Frame 030826/0825 →
CHANGE OF NAME Recorded Dec 21, 2011
From: SOLVAY PHARMACEUTICALS GMBH
To: ABBOTT PRODUCTS GMBH
Reel/Frame 027425/0611 →
RELEASE OF SECURITY INTEREST Recorded Jul 26, 2010
From: GOLDMAN SACHS CREDIT PARTNERS L.P., AS COLLATERAL AGENT
To: RELIANT PHARMACEUTICALS, INC.
Reel/Frame 024741/0060 →
SECURITY AGREEMENT Recorded May 9, 2007
From: RELIANT PHARMACEUTICALS, INC.
To: GOLDMAN SACHS CREDIT PARTNERS, L.P., AS COLLATERAL AGENT
Reel/Frame 019265/0086 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 2, 2005
From: VERBOOM, CEES-NICO; OELZE, RAINER
To: SOLVAY PHARMACEUTICALS GMBH
Reel/Frame 016647/0658 →