Apparatus and method for reducing subcutaneous fat deposits, virtual face lift and body sculpturing by electroporation
View Patent ↗An apparatus and method for performing non-invasive treatment of the human face and body by electroporation in lieu of cosmetic surgery is provided. The apparatus comprises a high voltage pulse generator and an applicator having two or more electrodes in close mechanical and electrical contact with the patient's skin for applying the pulses to the patient's skin. The applicator may consist of two pieces with one electrode having a sharp tip and another having a flat surface. High voltage pulses delivered to the electrodes create at the tip of the sharp electrode an electric field high enough to cause death of relatively large subcutaneous fat cells by electroporation. Moving the electrode tip along the skin creates a line of necrotic subcutaneous fat cells, which later are metabolized by the body. Multiple applications of the electrode along predetermined lines on the face or neck create shrinkage of the skin and the subcutaneous fat volume underlying the treated area.
1. A method for cosmetic treatment in lieu of cosmetic surgery, weight loss and/or body sculpturing comprising:
providing an applicator with a set of electrodes for engaging the skin of a patient and applying a pulsed electric field to the skin and the subcutaneous tissues of an area to be treated;
providing a power supply capable of generating high voltage pulses;
engaging patient's skin with the electrodes; and
applying a pulsed electric field to the area to be treated via the engaged electrodes in an amount sufficient to irreversibly open pores in the membranes of subcutaneous fat cells in the area to be treated, thereby causing death to the subcutaneous fat cells.
2. The method according to claim 1 , wherein the set of electrodes includes:
a first needle-like electrode and a second flat electrode; and
the step of applying a pulsed electric field includes applying electrical pulses between the needle-like electrode and the flat electrode.
3. The method according to claim 1 , wherein the set of electrodes includes:
a first electrode having a first polarity and a second electrode having a second polarity different from the first polarity; and
the step of applying a pulsed electric field includes applying electrical pulses between the first electrode and the second electrode.
4. The method according to claim 1 , wherein the applicator includes a pair of arms with respective electrode mounted on each arm, said arms being moveable toward and away from one another.
5. The method according to claim 1 , wherein the step of engaging includes positioning an array of electrodes near the area to be treated.
6. The method according to claim 1 , wherein the step of applying includes applying an electrical pulse whose amplitude is in the range of 20 Volt/mm and 2000 Volt/mm.
7. The method according to claim 1 , wherein the step of applying includes applying an electrical pulse whose amplitude is above 20 Volt/mm.
8. The method according to claim 1 , wherein the step of applying includes applying an electrical pulse whose duration is in a range of 10 microseconds and 100 milliseconds.
9. The method according to claim 1 , wherein the step of applying includes applying an electrical pulse whose amplitude is in the range of 20 Volt/mm and 2000 Volt/mm and whose duration is in a range of 10 microseconds and 100 milliseconds.
10. The method according to claim 1 , wherein:
the step of applying a pulsed electric field includes generating one or more magnetic pulses to thereby create a curl electric field in the fat cells.
11. The method according to claim 10 , wherein:
the step of generating one or more magnetic pulses includes generating one or more magnetic pulses with each having a duration in the range of 5 and 20 microseconds.
12. The method according to claim 10 , wherein:
the step of generating one or more magnetic pulses includes generating one or more magnetic pulses with each pulse creating a curl electric field in the range of 30 to 50 Volt/mm in the subcutaneous fat cells.
13. The method according to claim 1 , wherein:
the applicator includes an electromagnetic coil; and
the step of applying a pulsed electric field includes generating one or more magnetic pulses through the electromagnetic coil.
14. A method of destroying subcutaneous fat cells of a living mammal, comprising:
positioning an electric field applicator near a target area containing subcutaneous fat cells to be killed; and
applying an electric field through the positioned electric field applicator in an amount sufficient to irreversibly open pores in the membranes of the subcutaneous fat cells thereby causing death of the subcutaneous fat cells.
15. The method according to claim 14 , wherein:
the electric field applicator includes first and second electrodes;
the step of positioning includes positioning the first and second electrodes near the target area; and
the step of applying an electric field includes applying electrical pulses between the first and second electrodes.
16. The method according to claim 15 , wherein:
the first electrode is a needle-like electrode and the second electrode is a flat electrode; and
the step of applying an electric field includes applying the electrical pulses between the needle-like electrode and the flat electrode.
17. The method according to claim 15 , wherein:
the first electrode is an electrode having a first polarity and the second electrode is an electrode having a second polarity different from the first polarity; and
the step of applying includes applying the electrical pulses between the first electrode and the second electrode.
18. The method according to claim 14 , wherein the step of positioning includes positioning an array of electrodes near the target area.
19. The method according to claim 14 , wherein the step of applying includes applying an electrical pulse whose amplitude is in the range of 20 Volt/mm and 2000 Volt/mm.
20. The method according to claim 14 , wherein the step of applying includes applying an electrical pulse whose amplitude is above 20 Volt/mm.
21. The method according to claim 14 , wherein the step of applying includes applying an electrical pulse whose duration is in a range of 10 microseconds and 100 milliseconds.
22. The method according to claim 14 , wherein the step of applying includes applying an electrical pulse whose amplitude is in the range of 20 Volt/mm and 2000 Volt/mm and whose duration is in a range of 10 microseconds and 100 milliseconds.
23. The method according to claim 14 , wherein:
the step of applying an electric field includes generating one or more magnetic pulses to thereby create a curl electric field in the fat cells.
24. The method according to claim 23 , wherein:
the step of generating one or more magnetic pulses includes generating one or more magnetic pulses with each having a duration in the range of 5 and 20 microseconds.
25. The method according to claim 23 , wherein:
the step of generating one or more magnetic pulses includes generating one or more magnetic pulses with each pulse creating a curl electric field in the range of 30 to 50 Volt/mm in the subcutaneous fat cells.
26. The method according to claim 14 , wherein:
the electric field applicator includes an electromagnetic coil; and
the step of applying an electric field includes generating one or more magnetic pulses through the electromagnetic coil.