Acetyl L-carnitine for prevention of painful peripheral neuropathy in patients with type 2 diabetes
View Patent ↗Acetyl L-carnitine, or of one of its pharmaceutically acceptable salts, is useful for the prevention of painful peripheral neuropathy in patients suffering from type 2 diabetes, in which symptoms are pain, paraesthesia or hyperaesthesia. The acetyl L-carnitine is administered orally at a dose of at least 3 grams/day.
1. A method for treating and relieving symptoms of diabetic neuropathy in patients affected by type 2 diabetes, comprising administering to a patient in need thereof 3 grams/day of acetyl L-carnitine, or a pharmaceutically acceptable salt thereof for at least 52 weeks in which said symptoms are selected from the group consisting of pain, paraesthesia or hyperaesthesia.
2. The method according to claim 1 , in which the pharmaceutically acceptable salt of acetyl L-carnitine is selected from the group consisting of chloride, bromide, orotate, acid aspartate, acid citrate, magnesium citrate, acid phosphate, fumarate and acid fumarate, magnesium fumarate, lactate, maleate and acid maleate, mucate, acid oxalate, pamoate, acid pamoate, acid sulphate, glucose, phosphate, tartrate, acid tartrate, magnesium tartrate, 2-aminoethansulphonate, magnesium 2-ethansulphonate, choline tartrate and trichloroacetate.
3. The method according to claim 1 , in which the pharmaceutically acceptable salt of acetyl L-carnitine is a chloride salt.