Pyrrolobenzodiazepines
View Patent ↗A compound of formula I: or solvate thereof, wherein n is 1 to 10, and M and M′ are independently selected from monovalent pharmaceutically acceptable cations, or together represent a divalent pharmaceutically acceptable cation.
1. A compound of formula I:
wherein n is 1 to 10, and M and M′ are independently selected from monovalent pharmaceutically acceptable cations, or together represent a divalent pharmaceutically acceptable cation.
2. A compound according to claim 1 , wherein n is 1, 3, 6, 7 or 8.
3. A compound according to claim 2 , wherein n is 1 or 3.
4. The compound according to claim 1 , wherein M and M′ are the same.
5. The compound according to claim 4 , wherein each of M and M′ is an alkali metal ion.
6. The compound according to claim 5 , wherein each of M and M′ is Na + .
7. The compound of claim 1 , wherein the compound is purified or isolated.
8. A pharmaceutical composition comprising the compound of claim 1 and a pharmaceutically acceptable carrier.
9. A pharmaceutical composition comprising the compound of claim 2 and a pharmaceutically acceptable carrier.
10. A pharmaceutical composition comprising the compound of claim 3 and a pharmaceutically acceptable carrier.
11. A pharmaceutical composition comprising the compound of claim 4 and a pharmaceutically acceptable carrier.
12. A pharmaceutical composition comprising the compound of claim 5 and a pharmaceutically acceptable carrier.
13. A pharmaceutical composition comprising the compound of claim 6 and a pharmaceutically acceptable carrier.
14. A pharmaceutical composition comprising the compound of claim 7 and a pharmaceutically acceptable carrier.