IP Library › Granted Patent US 7,214,675
Granted Patent B2
US 7,214,675 · App. 11/132,546 · Granted May 8, 2007

Urea substituted imidazoquinoline ethers

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Quick Facts
Patent No.
US 7,214,675
App. No.
11/132,546
Granted
May 8, 2007
Kind
B2
Abstract

Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain ether and urea functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.

Claims (1)

1. A method of inducing cytokine biosynthesis in an animal comprising administering the compound N-{2-[2-(4-amino-2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl)ethoxy]ethyl}morpholine-4-carboxamide or a pharmaceutically acceptable salt thereof to the animal in an amount effective for cytokine induction wherein the cytokine is IFN-α and/or TNF-α.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 26, 2007
From: 3M INNOVATIVE PROPERTIES COMPANY
To: COLEY PHARMACEUTICAL GROUP, INC.
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