IP Library Patent Application 11136794
Patent Application
App. No. 11/136,794

Chromium/biotin treatment of dyslipidemia and diet-induced post prandial hyperglycemia

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Patent No.
US None
App. No.
11/136,794
Abstract

A method for treating dyslipidemia and/or post prandial hyperglycemia by administering a combination of a chromium complex and biotin to an individual in need thereof is disclosed. The two compounds are administered orally or parenterally in daily dosages which provide between 25 μg and 1,000 μg of chromium and between 25 μg and 20 mg biotin. A method for reducing the glycemic index of food is similarly provided.

Claims (35)

1 . A method for treating dyslipidemia consisting essentially of administering to an individual in need thereof a synergistically effective dose of a chromium complex and biotin.

2 . The method of claim 1 , wherein the synergistically effective dose of chromium complex is between about 25 and 2,000 micrograms per day.

3 . The method of claim 1 , wherein the synergistically effective dose of chromium complex is between about 300 and 1,000 micrograms per day.

4 . The method of claim 1 , wherein the synergistically effective dose of biotin is between about 25 μg and 20 mg per day.

5 . The method of claim 1 , wherein the synergistically effective dose of biotin is between about 150 μg and 5 mg.

6 . The method of claim 1 , wherein said dyslipidemia is caused by elevated levels of LDL cholesterol in the blood.

7 . The method of claim 1 , wherein said dyslipidemia is caused by low levels of HDL cholesterol in the blood.

8 . The method of claim 1 , wherein said dyslipidemia is caused by elevated levels of triglyceride in the blood.

9 . The method of claim 1 , wherein said chromium complex is selected from the group consisting of chromium picolinate, chromic tripicolinate, chromium nicotinate, chromic polynicotinate, chromium chloride, chromium histidinate, and chromium yeasts.

10 . The method of claim 1 , wherein said chromium complex is in a pharmaceutically acceptable carrier.

11 . The method of claim 1 , wherein said biotin is in a pharmaceutically acceptable carrier.

12 . The method of claim 1 , wherein said chromium complex is orally administered.

13 . The method of claim 1 , wherein said biotin is orally administered.

14 . The method of claim 1 , wherein said chromium complex is parenterally administered.

15 . The method of claim 1 , wherein said biotin is parenterally administered.

16 . The method of claim 1 , further comprising administering picolinic acid.

17 . The method of claim 1 , further comprising administering nicotinic acid.

18 . The method of claim 16 , further comprising administering nicotinic acid.

19 . The method of claim 1 , wherein said chromium complex and said biotin are administered simultaneously.

20 . The method of claim 1 , wherein said biotin is administered separately from said chromium complex.

21 . A method of reducing the glycemic index of food comprising administering to said food a synergistically effective amount of a chromium complex and biotin.

22 . The method of claim 21 , wherein said chromium complex is selected from the group consisting of chromium picolinate, chromic tripicolinate, chromium nicotinate, chromic polynicotinate, chromium chloride, chromium histidinate, and chromium yeasts.

23 . The method of claim 21 , wherein between about 25 and 1,000 micrograms of said chromium complex is administered to the food.

24 . The method of claim 21 , wherein between about 25 μg and 10 g of biotin are administered to the food.

25 . The method of claim 21 , wherein said chromium complex and said biotin are administered simultaneously.

26 . The method of claim 21 , wherein said chromium complex is added separately from said biotin complex.

27 . The method of claim 21 , wherein said chromium complex and said biotin are administered as a powder, liquid, oil suspension, granule, emulsion, syrup, elixir, or beverage.

28 . A food having a reduced glycemic index prepared by the method of claim 23 .

29 . A method for lowering post prandial hyperglycemia comprising administering to a subject in need thereof a synergistically effective amount of a chromium complex and biotin.

30 . The method of claim 29 , wherein said chromium complex is selected from the group consisting of chromium picolinate, chromic tripicolinate, chromium nicotinate, chromic polynicotinate, chromium chloride, chromium histidinate, and chromium yeasts.

31 . The method of claim 29 , wherein said subject is administered between about 25 and 2,000 micrograms per day of a chromium complex and between about 25 μg and 20 mg per day of biotin.

32 . The method of claim 29 , comprising administering between about 300 and 1,000 micrograms per day of a chromium complex.

33 . The method of claim 29 , comprising administering between about 150 μg and 5 mg biotin per day.

34 . The method of claim 29 , wherein said chromium complex and said biotin are administered simultaneously.

35 . The method of claim 29 , wherein said biotin is administered separately from said chromium complex.

Assignments (2)
CHANGE OF NAME Recorded Jun 14, 2012
From: N21 ACQUISITION HOLDING, LLC
To: JDS THERAPEUTICS, LLC
Reel/Frame 028603/0993 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 10, 2012
From: NUTRITION 21, INC.
To: N21 ACQUISITION HOLDING, LLC
Reel/Frame 027545/0079 →