Method for preventing or treating the development of respiratory allergies
View Patent ↗The present invention is directed to a novel method for preventing or treating the development of respiratory allergies. The method comprises prenatal and/or postnatal administration of a therapeutically effective amount of LGG.
1. A method for preventing the development of respiratory allergies in a subject, the method comprising prenatally administering and/or postnatally administering to the subject a therapeutically effective amount of LGG prior to allergic sensitization of the subject.
2. The method according to claim 1 , wherein the respiratory allergies are selected from the group consisting of allergic rhinitis, asthma and sinusitis.
3. The method according to claim 1 , wherein the prenatal administration of LGG comprises ingestion of LGG by the pregnant mother of the unborn subject.
4. The method according to claim 1 , wherein the postnatal administration of LGG comprises ingestion of LGG by the subject's mother and breast feeding of the subject by the mother.
5. The method according to claim 1 , wherein the postnatal administration of LGG comprises incorporation of the LGG into an infant formula and consumption of the formula by the subject.
6. The method according to claim 1 , wherein the postnatal administration of LGG continues for at least 3 months.
7. The method according to claim 1 , wherein the postnatal administration of LGG continues for at least 6 months.
8. The method according to claim 1 , wherein the postnatal administration of LGG continues for at least 1 year.
9. The method according to claim 1 , wherein the therapeutically effective amount of LGG is between about 1×10 4 and 1×10 10 cfu/L/kg/day.
10. The method according to claim 1 , wherein the therapeutically effective amount of LGG is between about 1×10 6 and 1×10 9 cfu/L/kg/day.
11. The method according to claim 1 , wherein the therapeutically effective amount of LGG is about 1×10 8 cfu/L/kg/day.
12. The method according to claim 1 , wherein the method additionally comprises prenatally and/or postnatally administering at least one other probiotic.
13. The method according to claim 1 , wherein the method additionally comprises prenatally and/or postnatally administering at least one prebiotic.
14. The method according to claim 1 , wherein the administration of LGG to the subject comprises incorporation of the LGG into an infant formula and consumption of the formula by the subject.