Hemostatic polymer useful for RAPID blood coagulation and hemostasis
Provided herein is a novel hemostatic polymer composition comprising a substance containing uncharged organic hydroxyl groups and a substance containing at least one of a halogen atom and an epoxy group, which is characterized as inducing rapid blood coagulation and hemostasis at a wound or bleeding site. Methods of use of the novel polymer composition are also provided.
1 - 44 . (canceled)
45 . A method for promoting blood coagulation at a bleeding site in a mammal comprising applying to said bleeding site a composition comprising porous polymeric spheres and allowing said blood coagulation to occur at said bleeding site.
46 . The method of claim 45 , wherein said mammal is a human.
47 . The method of claim 45 , wherein said porous polymeric spheres comprise a carbohydrate, a polysaccharide, or a polyol.
48 . The method of claim 47 , wherein said polysaccharide comprises dextran, starch, alginate, or cellulose.
49 . The method of claim 48 , wherein said polysaccharide comprises dextran.
50 . The method of claim 49 , wherein said dextran is cross-linked.
51 . The method of claim 50 , wherein said cross-linked dextran comprises HP-15.
52 . The method of claim 50 , wherein said cross-linked dextran comprises H-20.
53 . The method of claim 50 , wherein said cross-linked dextran comprises G-100.
54 . The method of claim 50 , wherein said cross-linked dextran comprises G-150.
55 . The method of claim 48 , wherein said polysaccharide comprises starch.
56 . A method for promoting blood coagulation at a bleeding site in a mammal comprising applying to said bleeding site a bandage comprising porous polymeric spheres and allowing said blood coagulation to occur at said bleeding site.
57 . The method of claim 56 , wherein said mammal is a human.
58 . The method of claim 56 , wherein said porous polymeric spheres comprise a carbohydrate, a polysaccharide, or a polyol.
59 . The method of claim 58 , wherein said polysaccharide comprises dextran, starch, alginate, or cellulose.
60 . The method of claim 59 , wherein said polysaccharide comprises dextran.
61 . The method of claim 60 , wherein said dextran is cross-linked.
62 . The method of claim 61 , wherein said cross-linked dextran comprises HP-15.
63 . The method of claim 61 , wherein said cross-linked dextran comprises G-150.
64 . The method of claim 59 , wherein said polysaccharide comprises starch.