Medical devices with magnetic resonance visibility enhancing material
The present invention relates to an elongated medical device for intralumenal manipulation during a process of magnetic resonance imaging. The device includes an elongated body. An extrusion material is integrated with the elongated body and includes a hydrophilic polymer that incorporates a substance having a plurality of paramagnetic ions. The extrusion material is configured to enhance magnetic resonance visibility during said process of magnetic resonance imaging.
1 - 28 . (canceled)
29 . A method of constructing a medical device, comprising:
co-extruding a composition and an elongated body, the composition comprising a hydrophilic polymer and a plurality of paramagnetic ions.
30 . The method of claim 29 , wherein the
plurality of paramagnetic ions comprise a paramagnetic metal salt, a paramagnetic metal chelate, or a paramagnetic metal complex.
31 . The method of claim 29 , wherein the medical device comprises: balloon.
32 . The method of claim 29 , wherein the plurality of paramagnetic ions comprises: a paramagnetic metal salt.
33 . The method of claim 29 , wherein the plurality of paramagnetic ions comprises: a gadolinium material.
34 . The method of claim 29 , wherein the plurality of paramagnetic ions comprises: a Gadolinium diethylenetriaminepentaacetic acid material.
35 . The method of claim 29 , comprising extruding the hydrophilic polymer on an inner lumen surface of the elongated body.
36 . The method of claim 29 , comprising extruding the hydrophilic polymer on an outer surface of the elongated body.
37 . The method of claim 29 , comprising extruding the hydrophilic polymer on an outer surface and an inner lumen surface of the elongated body.
38 . The method of claim 29 , wherein the hydrophilic polymer comprises a material selected from the group consisting of polyethylene oxide, polypropylene oxide, polyvinyl-pyrrolidone and hydrophilic polyurethane, polycarboxylic acids, cellulosic polymers, gelatin, maleic anhydride polymers, polyamides, polyvinyl alcohols, and polyacrylic acid.
39 . The method of claim 29 , further comprising
co-extruding a structural polymer in combination with the hydrophilic polymer.
40 . The method of claim 39 , wherein the structural polymer comprises a material selected from the group consisting of nylon, PEBAX, polyurethane, polyethylene, PEEK, polyimide, polyester-amide copolymer, and polyether-amide copolymer.
41 - 43 . (canceled)
44 . The method of claim 29 , further comprising:
cross-linking a portion of the polymer.
45 . The method of claim 29 , further comprising:
exposing at least one portion of the hydrophilic polymer and the plurality of paramagnetic ions incorporated therein.
46 . The method of claim 29 , further comprising applying a lubricious coating to the medical device.
47 . The method of claim 29 , further comprising applying a coating that contains a therapeutic agent to the medical device.
48 - 84 . (canceled)
85 . The method of claim 29 , wherein the composition is extruded in a striped pattern.
86 . The method of claim 29 , wherein the composition is extruded in a spiraled pattern.
87 . The method of claim 29 , wherein the medical device is a catheter.