IP Library Granted Patent US 7,385,068
Granted Patent B2
US 7,385,068 · App. 11/154,849 · Granted Jun 10, 2008

Stearate composition and method

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Quick Facts
Patent No.
US 7,385,068
App. No.
11/154,849
Granted
Jun 10, 2008
Kind
B2
Abstract

An improved alkaline earth metal stearate composition is disclosed and is prepared by reacting a fatty acid component including stearic acid and palmitic acid with an alkali hydroxide to form an alkaline soap. An aqueous metal salt solution is then added to the soap, and pH adjusted to less than about pH 8 to form the improved alkaline earth metal stearate. The improved alkaline earth metal stearate provides a substantially pure amount of the dihydrate form of the stearate.

Claims (26)

1. An alkaline earth metal stearate composition comprising alkaline earth metal stearate monohydrate and alkaline earth metal stearate dihydrate, the composition comprised of at least 40% earth metal stearate dihydrate and at least 5% palmitic acid, wherein the alkaline earth metal is selected from the group consisting magnesium and calcium.

2. The composition of claim 1 wherein the alkaline earth metal stearate composition is comprised of at least 70% alkaline earth metal stearate dihydrate.

3. The composition of claim 1 wherein the alkaline earth metal stearate composition is comprised of at least 99% alkaline earth metal stearate dihydrate.

4. A magnesium stearate composition comprising magnesium stearate monohydrate and magnesium stearate dihydrate and at least 5% palmitic acid, the composition comprised of at least 40% magnesium stearate dihydrate.

5. The composition of claim 4 wherein the magnesium stearate composition is comprised of at least 70% magnesium stearate dihydrate.

6. The composition of claim 4 wherein the magnesium stearate composition is comprised of at least 99% magnesium stearate dihydrate.

7. A method for preparing an alkaline earth metal stearate composition comprising alkaline earth metal stearate monohydrate and alkaline earth metal stearate dihydrate, the method comprising: providing a basic aqueous solution; incorporating at least one fatty acid, the fatty acid including at least 90% total stearic acid and palmitic acid, into the basic aqueous solution; adding at least one alkaline earth metal sulfate, whereby the alkaline earth metal stearate precipitates to form a slurry of the alkaline earth metal stearate composition; and adjusting the pH of the slurry to less than about pH 8 wherein the alkaline earth metal is selected from the group consisting of magnesium and calcium.

8. The method of claim 7 wherein the basic aqueous solution comprises water and NaOH.

9. The method of claim 7 wherein the pH of the slurry is adjusted to less than about pH 7.

10. The method of claim 7 wherein the pH of the slurry is adjusted to a pH of about 6.3 to a pH of about 6.4.

11. The method of claim 7 wherein the pH of the slurry is adjusted to a pH of about 5.0.

12. The method of claim 7 wherein the pH of the slurry is adjusted with an organic acid selected from the group consisting of sulfuric acid, hydrochloric acid, nitric acid and mixtures thereof.

13. The method of claim 7 wherein the pH of the slurry is adjusted as the alkaline earth metal stearate precipitates.

14. The method of claim 7 wherein the pH of the slurry is adjusted after the alkaline earth metal stearate precipitates.

15. The method of claim 7 further comprising performing a liquid-solid separation to remove the alkaline earth metal stearate composition from the slurry.

16. The method of claim 15 further comprising recovering the slurry for use in a subsequent preparation of alkaline earth metal stearate composition, wherein the recovered slurry is added to the basic aqueous solution.

17. A method for preparing a magnesium stearate composition comprising magnesium stearate monohydrate and magnesium stearate dihydrate, the method comprising: providing a basic aqueous solution; heating the basic aqueous solution; incorporating at least one fatty acid, the fatty acid including at least 90% total stearic acid and palmitic acid, into the basic aqueous solution, continuing heating the basic aqueous solution and the at least one fatty acid until the at least one fatty acid is dispersed within the basic aqueous solution; adding a solution of magnesium sulfate, whereby the magnesium sulfate reacts with the at least one fatty acid to form a slurry the magnesium stearate composition; and adjusting the pH of the slurry to less than a pH of about 8.

18. The method of claim 17 wherein the basic aqueous solution comprises water and NaOH.

19. The method of claim 17 wherein the pH is adjusted with an organic acid selected from the group consisting of sulfuric acid, hydrochloric acid, nitric acid and mixtures thereof.

20. The method of claim 17 wherein the pH of the slurry is adjusted to less than about 7.

21. The method of claim 17 wherein the pH of the slurry is adjusted to a pH of about 6.3 to about 6.4.

22. The method of claim 17 wherein the pH of the slurry is adjusted to a pH of about 5.0.

23. The method of claim 17 wherein the pH of the slurry is adjusted as the magnesium stearate composition precipitates.

24. The method of claim 17 wherein the pH of the slurry is adjusted after the magnesium stearate composition precipitates.

25. The method of claim 17 further comprising performing a liquid solid separation to recover the magnesium stearate composition from the slurry.

26. The method of claim 25 further comprising recovering the slurry for use in a subsequent preparation of alkaline earth metal stearate composition, wherein the recovered slurry is added to the basic aqueous solution.

Assignments (11)
RELEASE OF SECURITY INTEREST Recorded Aug 14, 2025
From: ACQUIOM AGENCY SERVICES LLC
To: MALLINCKRODT ENTERPRISES LLC; MALLINCKRODT LLC; MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY; MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED; OCERA THERAPEUTICS LLC; SPECGX LLC; STRATATECH CORPORATION; SUCAMPO PHARMA AMERICAS LLC; VTESSE LLC
Reel/Frame 072324/0740 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Jul 31, 2025
From: SPECGX LLC
To: WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT
Reel/Frame 072313/0063 →
RELEASE OF PATENT SECURITY INTERESTS RECORDED AT REEL 032480, FRAME 0001 Recorded Nov 16, 2023
From: DEUTSCHE BANK AG NEW YORK BRANCH, AS COLLATERAL AGENT
To: THERAKOS, INC.; MALLINCKRODT INTERNATIONAL FINANCE S.A.; MALLINCKRODT CB LLC; MALLINCKRODT FINANCE GMBH; MALLINCKRODT US HOLDINGS LLC (F/K/A MALLINCKRODT US HOLDINGS INC.); MALLINCKRODT CARRIBEAN, INC.; MALLINCKRODT US POOL LLC; MNK 2011 LLC (F/K/A MALLINCKRODT INC.); LUDLOW LLC (F/K/A LUDLOW CORPORATION); CNS THERAPEUTICS, INC.; MALLINCKRODT ENTERPRISES HOLDINGS LLC (F/K/A MALLINCKRODT ENTERPRISES HOLDINGS, INC.); MALLINCKRODT ENTERPRISES LLC; MALLINCKRODT LLC; LAFAYETTE PHARMACEUTICALS LLC; LIEBEL-FLARSHEIM COMPANY LLC; MALLINCKRODT BRAND PHARMACEUTICALS LLC (F/K/A MALLINCKRODT BRAND PHARMACEUTICALS, INC.); MALLINCKRODT VETERINARY, INC.; MALLINCKRODT US HOLDINGS LLC; IMC EXPLORATION COMPANY; MEH, INC.; MALLINCKRODT HOSPITAL PRODUCTS IP UNLIMITED COMPANY (F/K/A MALLINCKRODT HOSPITAL PRODUCTS IP LIMITED); MALLINCKRODT ARD IP UNLIMITED COMPANY (F/K/A MALLINCKRODT ARD IP LIMITED); OCERA THERAPEUTICS LLC (F/K/A OCERA THERAPEUTICS, INC.); SPECGX LLC; STRATATECH CORPORATION; SUCAMPO PHARMA AMERICAS LLC; VTESSE LLC (F/K/A VTESSE INC.); MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED; MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY (F/K/A MALLINCKRODT PHARMA IP TRADING D.A.C.); INFACARE PHARMACEUTICAL CORPORATION; ST SHARED SERVICES LLC; IKARIA THERAPEUTICS LLC; INO THERAPEUTICS LLC
Reel/Frame 065609/0322 →
RELEASE OF PATENT SECURITY INTERESTS RECORDED AT REEL 060434, FRAME 0536 Recorded Nov 16, 2023
From: DEUTSCHE BANK AG NEW YORK BRANCH, AS COLLATERAL AGENT
To: MALLINCKRODT ENTERPRISES LLC; MALLINCKRODT LLC; SPECGX LLC; OCERA THERAPEUTICS, INC.; STRATATECH CORPORATION; VTESSE LLC; MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY; MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED; SUCAMPO PHARMA AMERICAS LLC
Reel/Frame 065601/0347 →
SECURITY INTEREST Recorded Nov 15, 2023
From: MALLINCKRODT ENTERPRISES LLC; MALLINCKRODT LLC; MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY; MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED; OCERA THERAPEUTICS LLC; SPECGX LLC; STRATATECH CORPORATION; SUCAMPO PHARMA AMERICAS LLC; VTESSE LLC
To: ACQUIOM AGENCY SERVICES LLC
Reel/Frame 065595/0376 →
RELEASE OF SECURITY INTERESTS IN PATENTS AT REEL 060389/FRAME 0913 Recorded Nov 15, 2023
From: WILMINGTON SAVINGS FUND SOCIETY, FSB, AS SECOND LIEN COLLATERAL AGENT
To: OCERA THERAPEUTICS LLC (F/K/A OCERA THERAPEUTICS, INC.); MALLINCKRODT LLC; MALLINCKRODT ENTERPRISES LLC; MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY; SPECGX LLC; STRATATECH CORPORATION; SUCAMPO PHARMA AMERICAS LLC; VTESSE LLC; MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED
Reel/Frame 065583/0465 →
NOTICE OF GRANT OF SECURITY INTEREST IN INTELLECTUAL PROPERTY Recorded Jun 22, 2022
From: MALLINCKRODT ENTERPRISES LLC; MALLINCKRODT LLC; SPECGX LLC; OCERA THERAPEUTICS, INC.; STRATATECH CORPORATION; SUCAMPO PHARMA AMERICAS LLC; VTESSE LLC; MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED; MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY
To: DEUTSCHE BANK AG NEW YORK BRANCH
Reel/Frame 060434/0536 →
SECURITY INTEREST Recorded Jun 17, 2022
From: MALLINCKRODT ENTERPRISES LLC; MALLINCKRODT LLC; SPECGX LLC; OCERA THERAPEUTICS, INC.; STRATATECH CORPORATION; SUCAMPO PHARMA AMERICAS LLC; VTESSE LLC; MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED
To: WILMINGTON SAVINGS FUND SOCIETY, FSB, AS SECOND LIEN COLLATERAL AGENT
Reel/Frame 060389/0913 →
RELEASE OF SECURITY INTEREST Recorded Jun 17, 2022
From: WILMINGTON SAVINGS FUND SOCIETY, FSB, AS SECOND LIEN COLLATERAL AGENT
To: OCERA THERAPEUTICS, INC.; MALLINCKRODT LLC; MALLINCKRODT ARD IP UNLIMITED COMPANY (F/K/A MALLINCKRODT ARD IP LIMITED); MALLINCKRODT HOSPITAL PRODUCTS IP UNLIMITED COMPANY (F/K/A MALLINCKRODT HOSPITAL PRODUCTS IP LIMITED); MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY (F/K/A MALLINCKRODT PHARMA IP TRADING DESIGNATED ACTIVITY COMPANY); SPECGX LLC; STRATATECH CORPORATION; VTESSE LLC (F/K/A VTESSE INC.)
Reel/Frame 060389/0839 →
SECURITY INTEREST Recorded Dec 10, 2019
From: MALLINCKRODT ARD IP LIMITED; MALLINCKRODT HOSPITAL PRODUCTS IP LIMITED; SPECGX LLC; OCERA THERAPEUTICS, INC.; MALLINCKRODT PHARMA IP TRADING DESIGNATED ACTIVITY COMPANY; STRATATECH CORPORATION; VTESSE INC.; MALLINCKRODT LLC
To: WILMINGTON SAVINGS FUND SOCIETY, FSB, AS SECOND LIEN COLLATERAL AGENT
Reel/Frame 051256/0829 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 13, 2017
From: MALLINCKRODT LLC
To: SPECGX LLC
Reel/Frame 044891/0376 →